Management of squamous cell carcinoma of the head and neck in the elderly: Review and recommendations

Alva Weir; Apar Kishor Ganti; Mollie deShazo; Sandeep Samant; Arti Hurria

doi:10.1016/j.jgo.2012.02.010

Management of squamous cell carcinoma of the head and neck in the elderly: Review and recommendations

Alva Weir^*, Apar Kishor Ganti, Mollie deShazo, Sandeep Samant, Arti Hurria

^*Corresponding author for this work

Otolaryngology

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

In general, the management and reported outcomes for elderly patients with squamous cell carcinoma of the head and neck (SCCHN) have been similar to those of younger patients. But older adults are a distinct subpopulation of patients who differ from younger patients due to their increased risks for: comorbidities, decreased functional status, a potential decline in cognitive function and an increase in vulnerabilities. Older adults have been underrepresented in the clinical trials which define our best treatment strategies. This review explores the evidence used to establish common practice in managing SCCHN and evaluates the relevance of this evidence for the older adult, concluding with recommendations based on the review.

Original language	English (US)
Pages (from-to)	265-272
Number of pages	8
Journal	Journal of Geriatric Oncology
Volume	3
Issue number	3
DOIs	https://doi.org/10.1016/j.jgo.2012.02.010
State	Published - Jul 2012

Keywords

Chemotherapy
Elderly
Geriatric Assessment
Radiation
Squamous cell carcinoma of the head and neck
Surgery
Therapy

ASJC Scopus subject areas

Oncology
Geriatrics and Gerontology

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10.1016/j.jgo.2012.02.010

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title = "Management of squamous cell carcinoma of the head and neck in the elderly: Review and recommendations",

abstract = "In general, the management and reported outcomes for elderly patients with squamous cell carcinoma of the head and neck (SCCHN) have been similar to those of younger patients. But older adults are a distinct subpopulation of patients who differ from younger patients due to their increased risks for: comorbidities, decreased functional status, a potential decline in cognitive function and an increase in vulnerabilities. Older adults have been underrepresented in the clinical trials which define our best treatment strategies. This review explores the evidence used to establish common practice in managing SCCHN and evaluates the relevance of this evidence for the older adult, concluding with recommendations based on the review.",

keywords = "Chemotherapy, Elderly, Geriatric Assessment, Radiation, Squamous cell carcinoma of the head and neck, Surgery, Therapy",

author = "Alva Weir and Ganti, {Apar Kishor} and Mollie deShazo and Sandeep Samant and Arti Hurria",

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T2 - Review and recommendations

AU - Weir, Alva

AU - Ganti, Apar Kishor

AU - deShazo, Mollie

AU - Samant, Sandeep

AU - Hurria, Arti

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N2 - In general, the management and reported outcomes for elderly patients with squamous cell carcinoma of the head and neck (SCCHN) have been similar to those of younger patients. But older adults are a distinct subpopulation of patients who differ from younger patients due to their increased risks for: comorbidities, decreased functional status, a potential decline in cognitive function and an increase in vulnerabilities. Older adults have been underrepresented in the clinical trials which define our best treatment strategies. This review explores the evidence used to establish common practice in managing SCCHN and evaluates the relevance of this evidence for the older adult, concluding with recommendations based on the review.

AB - In general, the management and reported outcomes for elderly patients with squamous cell carcinoma of the head and neck (SCCHN) have been similar to those of younger patients. But older adults are a distinct subpopulation of patients who differ from younger patients due to their increased risks for: comorbidities, decreased functional status, a potential decline in cognitive function and an increase in vulnerabilities. Older adults have been underrepresented in the clinical trials which define our best treatment strategies. This review explores the evidence used to establish common practice in managing SCCHN and evaluates the relevance of this evidence for the older adult, concluding with recommendations based on the review.

KW - Chemotherapy

KW - Elderly

KW - Geriatric Assessment

KW - Radiation

KW - Squamous cell carcinoma of the head and neck

KW - Surgery

KW - Therapy

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Management of squamous cell carcinoma of the head and neck in the elderly: Review and recommendations

Abstract

Keywords

ASJC Scopus subject areas

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