Management of water imbalance in schizophrenia

Morris Goldman*, Pichai Ittasakul

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations


In this chapter, we review the epidemiology of polydipsia, mild/moderate chronic hyponatremia, and episodic water intoxication in schizophrenia. We then summarize the clinical presentation, paying particular attention to unique clinical features of the psychosis, intermittent hyponatremia, polydipsia (PIP) syndrome. Next we address the diagnosis and differential diagnosis of water imbalance in this population, and summarize what is known about the pathophysiology of primary polydipsia and the PIP syndrome. Finally, we discuss treatment options.

Original languageEnglish (US)
Title of host publicationSchizophrenia
Subtitle of host publicationRecent Advances in Diagnosis and Treatment
PublisherSpringer New York
Number of pages19
ISBN (Electronic)9781493906567
ISBN (Print)1493906550, 9781493906550
StatePublished - Feb 1 2014

ASJC Scopus subject areas

  • General Medicine


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