TY - JOUR
T1 - Managing seborrheic keratosis
T2 - Evolving strategies and optimal therapeutic outcomes
AU - Kao, Stephanie
AU - Kiss, Alexi
AU - Efimova, Tatiana
AU - Friedman, Adam J.
N1 - Funding Information:
Disclosure of Commercial Support: This activity is supported by an educational grant provided by Aclaris Therapeutics Inc.
Publisher Copyright:
© 2018 Journal of Drugs in Dermatology. All rights reserved.
PY - 2018/9
Y1 - 2018/9
N2 - Seborrheic keratosis (SK) is the most common skin tumor seen by dermatologists in everyday practice. Although the lesions are mostly benign, many patients still elect to have asymptomatic SK removed. The historical standards of treatment are cryosurgery and electrocautery, two surgical options that are effective at lesion removal but have high rates of postoperative adverse events such as treatment-site scarring and pigmentary alterations. The cosmetic outcomes of SK treatment modalities are of keen interest to dermatologists, as the American population becomes increasingly more diverse. In this article, the inclusion of darker Fitzpatrick skin types into clinical studies investigating post-treatment side effects of SK therapy is reviewed. The recent approval of a 40% hydrogen peroxide topical formulation is discussed in light of these issues, and several non-invasive topical treatments that optimize cosmetic outcomes of SK lesion removal are highlighted. Finally, treatment strategies aimed at reducing cost and minimizing the burden of adverse sequelae are provided.
AB - Seborrheic keratosis (SK) is the most common skin tumor seen by dermatologists in everyday practice. Although the lesions are mostly benign, many patients still elect to have asymptomatic SK removed. The historical standards of treatment are cryosurgery and electrocautery, two surgical options that are effective at lesion removal but have high rates of postoperative adverse events such as treatment-site scarring and pigmentary alterations. The cosmetic outcomes of SK treatment modalities are of keen interest to dermatologists, as the American population becomes increasingly more diverse. In this article, the inclusion of darker Fitzpatrick skin types into clinical studies investigating post-treatment side effects of SK therapy is reviewed. The recent approval of a 40% hydrogen peroxide topical formulation is discussed in light of these issues, and several non-invasive topical treatments that optimize cosmetic outcomes of SK lesion removal are highlighted. Finally, treatment strategies aimed at reducing cost and minimizing the burden of adverse sequelae are provided.
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M3 - Article
C2 - 30235378
AN - SCOPUS:85060704404
SN - 1545-9616
VL - 17
SP - 931
EP - 940
JO - Journal of Drugs in Dermatology
JF - Journal of Drugs in Dermatology
IS - 9
ER -