Abstract
Conformational differences between manganese hemoglobin and its liganded derivatives are observed in the tetramer-dimer dissociation equilibrium, in the binding of 8-hydroxy-1,3,6-pyrenetrisulfonate (an analogue of 2,3-diphosphoglycerate) and bromthymol blue, and in the reaction with p-hydroxymercuribenzoate. The reaction of manganese hemoglobin with NO is readily followed by stopped flow, the resulting NO derivative is photodissociable, and rapid kinetic measurements exhibit the hemoglobin allosteric interaction.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 146-151 |
| Number of pages | 6 |
| Journal | Biochemical and Biophysical Research Communications |
| Volume | 59 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jul 10 1974 |
ASJC Scopus subject areas
- Biophysics
- Biochemistry
- Molecular Biology
- Cell Biology
Fingerprint Dive into the research topics of 'Manganese hemoglobin: Allosteric effects in stopped flow flash photolysis and sedimentation measurements'. Together they form a unique fingerprint.
Cite this
Gibson, Q. H., Hoffman, B. M., Crepeau, R. H., Edelstein, S. J., & Bull, C. (1974). Manganese hemoglobin: Allosteric effects in stopped flow flash photolysis and sedimentation measurements. Biochemical and Biophysical Research Communications, 59(1), 146-151. https://doi.org/10.1016/S0006-291X(74)80186-5