Mapping acute lesion locations to physiological swallow impairments after stroke

Janina Wilmskoetter*, Leonardo Bonilha, Bonnie Martin-Harris, Jordan J. Elm, Janet Horn, Heather S. Bonilha

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

36 Scopus citations


Dysphagia is a common deficit after a stroke, and it is frequently associated with pneumonia, malnutrition, dehydration, and poor quality of life. It is not yet fully clear which brain regions are directly related to swallowing, and how lesions affect swallow physiology. This study aimed to assess the statistical relationship between acute stroke lesion locations and impairment of specific aspects of swallow physiology. We performed lesion symptom mapping with 68 retrospectively recruited, acute, first-ever ischemic stroke patients. Lesions were determined on diffusion weighted MRI scans. Post-stroke swallow physiology was determined using the Modified Barium Swallow Study Impairment Profile (MBSImP

Original languageEnglish (US)
Article number101685
JournalNeuroImage: Clinical
StatePublished - Jan 1 2019


  • Deglutition
  • Deglutition disorders
  • Lesion analysis
  • Magnetic resonance imaging
  • Stroke

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Neurology
  • Clinical Neurology
  • Cognitive Neuroscience


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