TY - JOUR
T1 - Mapping acute lesion locations to physiological swallow impairments after stroke
AU - Wilmskoetter, Janina
AU - Bonilha, Leonardo
AU - Martin-Harris, Bonnie
AU - Elm, Jordan J.
AU - Horn, Janet
AU - Bonilha, Heather S.
N1 - Funding Information:
Janina Wilmskoetter receives salary from the Medical University of South Carolina. Leonardo Bonilha reports no disclosures. Bonnie Martin-Harris is funded by NIH / NIDCD grants # 1K24DC12801 and # 1R01DC011290 , receives research support from Bracco Diagnostics, and holds copyright royalties from Northern Speech Services and the Medical University of South Carolina. Jordan J. Elm reports no disclosures. Janet Horn receives a stipend/salary from the Medical University of South Carolina. Heather S. Bonilha is funded by NIH / NIDDK grant # R01 DK098222 , by the Center for Biomedical Research Excellence (COBRE) in Stroke Recovery at the Medical University of South Carolina (MUSC) in Charleston, South Carolina, #5P20GM109040, serves as an editorial board member for ASHA journal, serves as a grant reviewer for NIH, and receives salary from the Medical University of South Carolina.
Funding Information:
The project described was supported in part by the National Institutes of Health / National Center for Advancing Translational Sciences (NCATS) through Grant Number UL1 TR001450 , SCTR Pilot Project 17254, Center for Biomedical Research Excellence (COBRE) in Stroke Recovery at the Medical University of South Carolina (MUSC) in Charleston, South Carolina through Grant Number 5P20GM109040 , and National Institutes of Health / National Institute on Deafness and Other Communication Disorders (NIDCD) through Grant Number T32DC014435 .
Publisher Copyright:
© 2019 The Authors
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Dysphagia is a common deficit after a stroke, and it is frequently associated with pneumonia, malnutrition, dehydration, and poor quality of life. It is not yet fully clear which brain regions are directly related to swallowing, and how lesions affect swallow physiology. This study aimed to assess the statistical relationship between acute stroke lesion locations and impairment of specific aspects of swallow physiology. We performed lesion symptom mapping with 68 retrospectively recruited, acute, first-ever ischemic stroke patients. Lesions were determined on diffusion weighted MRI scans. Post-stroke swallow physiology was determined using the Modified Barium Swallow Study Impairment Profile (MBSImP
AB - Dysphagia is a common deficit after a stroke, and it is frequently associated with pneumonia, malnutrition, dehydration, and poor quality of life. It is not yet fully clear which brain regions are directly related to swallowing, and how lesions affect swallow physiology. This study aimed to assess the statistical relationship between acute stroke lesion locations and impairment of specific aspects of swallow physiology. We performed lesion symptom mapping with 68 retrospectively recruited, acute, first-ever ischemic stroke patients. Lesions were determined on diffusion weighted MRI scans. Post-stroke swallow physiology was determined using the Modified Barium Swallow Study Impairment Profile (MBSImP
KW - Deglutition
KW - Deglutition disorders
KW - Lesion analysis
KW - Magnetic resonance imaging
KW - Stroke
UR - http://www.scopus.com/inward/record.url?scp=85060750916&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85060750916&partnerID=8YFLogxK
U2 - 10.1016/j.nicl.2019.101685
DO - 10.1016/j.nicl.2019.101685
M3 - Article
C2 - 30711683
AN - SCOPUS:85060750916
VL - 22
JO - NeuroImage: Clinical
JF - NeuroImage: Clinical
SN - 2213-1582
M1 - 101685
ER -
