Mapping Community-Engaged Implementation Strategies with Transgender Scientists, Stakeholders, and Trans-Led Community Organizations

Arjee Restar*, Brian J. Minalga, Ma Irene Quilantang, Tyler Adamson, Emerson Dusic, Leigh Ann van der Merwe, Greg Millet, Danvic Rosadiño, Tanya Laguing, Elle Lett, Avery Everhart, Gregory Phillips, Rena Janamnuaysook, Pich Seekaew, Kellan Baker, Florence Ashley, Jeffrey Wickersham, Stephaun E. Wallace, Don Operario, Kristi E. Gamarel

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

24 Scopus citations

Abstract

Purpose of Review: Pre-exposure prophylaxis (PrEP) represents one of the most effective methods of prevention for HIV, but remains inequitable, leaving many transgender and nonbinary (trans) individuals unable to benefit from this resource. Deploying community-engaged PrEP implementation strategies for trans populations will be crucial for ending the HIV epidemic. Recent Findings: While most PrEP studies have progressed in addressing pertinent research questions about gender-affirming care and PrEP at the biomedical and clinical levels, research on how to best implement gender-affirming PrEP systems at the social, community, and structural levels remains outstanding. Summary: The science of community-engaged implementation to build gender-affirming PrEP systems must be more fully developed. Most published PrEP studies with trans people report on outcomes rather than processes, leaving out important lessons learned about how to design, integrate, and implement PrEP in tandem with gender-affirming care. The expertise of trans scientists, stakeholders, and trans-led community organizations is essential to building gender-affirming PrEP systems.

Original languageEnglish (US)
Pages (from-to)160-169
Number of pages10
JournalCurrent HIV/AIDS Reports
Volume20
Issue number3
DOIs
StatePublished - Jun 2023

Funding

Dr. Restar is supported by the Research Education Institute for Diverse Scholars (REIDS) Program at Yale University School of Public Health, funded by the National Institute of Mental Health (R25MH087217). Additional support was provided by R01MH115765 (Drs. Kristi Gamarel and Don Operario) from the National Institute of Mental Health (NIMH) and R21TW012010 (Dr. Don Operario) from the Fogarty International Center (FIC). This article does not represent the official views of the sponsors. Rena Janamnuaysook has received research funding from Gilead Sciences, and speaker fees from ViiV Healthcare. Dr. Stephaun Wallace reports research funding from NIH/NIAID, Johnson and Johnson/Janssen, and Gilead. Dr. Leigh-Ann van der Merwe reports involvement as global community advisory group for Gilead’s Lenacapavir trial for transgender women. Arjee Restar, Brian J. Minalga, Ma Irene Quilantang, Tyler Adamson, Emerson Dusic, Greg Millet, Danvic Rosadiño, Tanya Laguing, Elle Lett, Avery Everhart, Gregory Phillips II, Pich Seekaew, Kellan Baker, Florence Ashley, Jeffrey Wickersham, Don Operario, and Kristi E. Gamarel, PhD, declare that they have no conflict of interest.

Keywords

  • Gender-affirming care
  • HIV prevention
  • Implementation
  • Nonbinary
  • PrEP
  • Transgender

ASJC Scopus subject areas

  • Virology
  • Infectious Diseases

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