Mapping of polypeptide encoded by the Epstein-Barr virus genome in productive infection

M. Hummel, E. Kieff

Research output: Contribution to journalArticlepeer-review

36 Scopus citations

Abstract

Over 30 viral-specified polypeptides are translated in vitro from RNA of cells productively infected with Epstein-Barr virus (EBV). The polypeptides map to sites in EBV DNA by hybrid selection. Almost all of the polypeptides are reactive with EBV immune human serum. Several of the polypeptides are part of the early antigen complex. Two others are likely to be major structural components of the virus. Genes encoding persistent early and late polypeptides are intermixed through most of the EBV genome.

Original languageEnglish (US)
Pages (from-to)5698-5702
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Volume79
Issue number18 I
DOIs
StatePublished - 1982

ASJC Scopus subject areas

  • General

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