Marked differences in quantity of infectious human immunodeficiency virus type 1 detected in persons with controlled plasma viremia by a simple enhanced culture method

C. L. Tremblay, F. Giguel, D. P. Merrill, J. T. Wong, E. Rosenberg, S. Kalams, B. D. Walker, R. T. D'Aquila, M. S. Hirsch*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Culture of autologous CD4 lymphocytes from peripheral blood mononuclear cells compared favorably with two other methods for the measurement of cell-associated human immunodeficiency virus type 1 (HIV-1). For subjects with undetectable HIV-1 RNA levels in plasma, there was a 10,000-fold range of cell-associated virus detected. This method provides a simple and reproducible means for monitoring cell-associated HIV-1.

Original languageEnglish (US)
Pages (from-to)4246-4248
Number of pages3
JournalJournal of clinical microbiology
Volume38
Issue number11
DOIs
StatePublished - 2000

ASJC Scopus subject areas

  • Microbiology (medical)

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