Marked differences in quantity of infectious human immunodeficiency virus type 1 detected in persons with controlled plasma viremia by a simple enhanced culture method

C. L. Tremblay; F. Giguel; D. P. Merrill; J. T. Wong; E. Rosenberg; S. Kalams; B. D. Walker; R. T. D'Aquila; M. S. Hirsch

doi:10.1128/jcm.38.11.4246-4248.2000

Marked differences in quantity of infectious human immunodeficiency virus type 1 detected in persons with controlled plasma viremia by a simple enhanced culture method

C. L. Tremblay, F. Giguel, D. P. Merrill, J. T. Wong, E. Rosenberg, S. Kalams, B. D. Walker, R. T. D'Aquila, M. S. Hirsch^*

^*Corresponding author for this work

Medicine, Infectious Diseases Division

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Culture of autologous CD4 lymphocytes from peripheral blood mononuclear cells compared favorably with two other methods for the measurement of cell-associated human immunodeficiency virus type 1 (HIV-1). For subjects with undetectable HIV-1 RNA levels in plasma, there was a 10,000-fold range of cell-associated virus detected. This method provides a simple and reproducible means for monitoring cell-associated HIV-1.

Original language	English (US)
Pages (from-to)	4246-4248
Number of pages	3
Journal	Journal of clinical microbiology
Volume	38
Issue number	11
DOIs	https://doi.org/10.1128/jcm.38.11.4246-4248.2000
State	Published - 2000

ASJC Scopus subject areas

Microbiology (medical)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1128/jcm.38.11.4246-4248.2000

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Tremblay, C. L., Giguel, F., Merrill, D. P., Wong, J. T., Rosenberg, E., Kalams, S., Walker, B. D., D'Aquila, R. T., & Hirsch, M. S. (2000). Marked differences in quantity of infectious human immunodeficiency virus type 1 detected in persons with controlled plasma viremia by a simple enhanced culture method. Journal of clinical microbiology, 38(11), 4246-4248. https://doi.org/10.1128/jcm.38.11.4246-4248.2000

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abstract = "Culture of autologous CD4 lymphocytes from peripheral blood mononuclear cells compared favorably with two other methods for the measurement of cell-associated human immunodeficiency virus type 1 (HIV-1). For subjects with undetectable HIV-1 RNA levels in plasma, there was a 10,000-fold range of cell-associated virus detected. This method provides a simple and reproducible means for monitoring cell-associated HIV-1.",

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Tremblay, CL, Giguel, F, Merrill, DP, Wong, JT, Rosenberg, E, Kalams, S, Walker, BD, D'Aquila, RT & Hirsch, MS 2000, 'Marked differences in quantity of infectious human immunodeficiency virus type 1 detected in persons with controlled plasma viremia by a simple enhanced culture method', Journal of clinical microbiology, vol. 38, no. 11, pp. 4246-4248. https://doi.org/10.1128/jcm.38.11.4246-4248.2000

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T1 - Marked differences in quantity of infectious human immunodeficiency virus type 1 detected in persons with controlled plasma viremia by a simple enhanced culture method

AU - Tremblay, C. L.

AU - Giguel, F.

AU - Merrill, D. P.

AU - Wong, J. T.

AU - Rosenberg, E.

AU - Kalams, S.

AU - Walker, B. D.

AU - D'Aquila, R. T.

AU - Hirsch, M. S.

PY - 2000

Y1 - 2000

N2 - Culture of autologous CD4 lymphocytes from peripheral blood mononuclear cells compared favorably with two other methods for the measurement of cell-associated human immunodeficiency virus type 1 (HIV-1). For subjects with undetectable HIV-1 RNA levels in plasma, there was a 10,000-fold range of cell-associated virus detected. This method provides a simple and reproducible means for monitoring cell-associated HIV-1.

AB - Culture of autologous CD4 lymphocytes from peripheral blood mononuclear cells compared favorably with two other methods for the measurement of cell-associated human immunodeficiency virus type 1 (HIV-1). For subjects with undetectable HIV-1 RNA levels in plasma, there was a 10,000-fold range of cell-associated virus detected. This method provides a simple and reproducible means for monitoring cell-associated HIV-1.

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Marked differences in quantity of infectious human immunodeficiency virus type 1 detected in persons with controlled plasma viremia by a simple enhanced culture method

Abstract

ASJC Scopus subject areas

UN SDGs

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