Masking of Infrared Neural Stimulation (INS) in hearing and deaf guinea pigs

Sama Kadakia, Hunter Young, Claus-Peter Richter

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Scopus citations


Spatial selective infrared neural stimulation has potential to improve neural prostheses, including cochlear implants. The heating of a confined target volume depolarizes the cell membrane and results in an action potential. Tissue heating may also results in thermal damage or the generation of a stress relaxation wave. Stress relaxation waves may result in a direct mechanical stimulation of remaining hair cells in the cochlea, so called optophony. Data are presented that quantify the effect of an acoustical stimulus (noise masker) on the response obtained with INS in normal hearing, acutely deafened, and chronic deaf animals. While in normal hearing animals an acoustic masker can reduce the response to INS, in acutely deafened animals the masking effect is reduced, and in chronic deaf animals this effect has not been detected. The responses to INS remain stable following the different degrees of cochlear damage.

Original languageEnglish (US)
Title of host publicationPhotonic Therapeutics and Diagnostics IX
StatePublished - May 30 2013
EventPhotonic Therapeutics and Diagnostics IX - San Francisco, CA, United States
Duration: Feb 2 2013Feb 7 2013

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


OtherPhotonic Therapeutics and Diagnostics IX
Country/TerritoryUnited States
CitySan Francisco, CA


  • Cochlea
  • Hearing
  • Infrared neural stimulation
  • Laser
  • Masking

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging


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