Maternal plasma concentrations on insulin-like growth factor-I (IGF-I) and human placental lactogen (hPL) in twin pregnancies

R. R. Kazer; E. R. Cheng; T. G. Unterman; R. P. Glick

doi:10.1017/s0001566000003573

Maternal plasma concentrations on insulin-like growth factor-I (IGF-I) and human placental lactogen (hPL) in twin pregnancies

R. R. Kazer^*, E. R. Cheng, T. G. Unterman, R. P. Glick

^*Corresponding author for this work

Obstetrics and Gynecology

Research output: Contribution to journal › Article › peer-review

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Abstract

Maternal plasma IGF-I and hPL concentrations were examined in 10 singleton pregnancies and in 11 twin gestations near term. hPL concentrations were higher in the twin pregnancies (14.4 ± 2.4 μg/l vs 6.9 ± 0.9 μg/l, P < 0.02). In contrast, plasma IGF-I concentrations were similar in the singleton and twin pregnancies (533 ± 45 μg/l vs 572 ± 60 μg/l, respectively). IGF-I concentrations failed to correlate with hPL concentrations in either group separately or when all subjects were considered together. These data do not support the hypothesis that maternal IGF-I secretion is an hPL-dependent process.

Original language	English (US)
Pages (from-to)	383-387
Number of pages	5
Journal	Acta Geneticae Medicae et Gemellologiae
Volume	40
Issue number	3-4
DOIs	https://doi.org/10.1017/s0001566000003573
State	Published - 1991

ASJC Scopus subject areas

Genetics(clinical)

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title = "Maternal plasma concentrations on insulin-like growth factor-I (IGF-I) and human placental lactogen (hPL) in twin pregnancies",

abstract = "Maternal plasma IGF-I and hPL concentrations were examined in 10 singleton pregnancies and in 11 twin gestations near term. hPL concentrations were higher in the twin pregnancies (14.4 ± 2.4 μg/l vs 6.9 ± 0.9 μg/l, P < 0.02). In contrast, plasma IGF-I concentrations were similar in the singleton and twin pregnancies (533 ± 45 μg/l vs 572 ± 60 μg/l, respectively). IGF-I concentrations failed to correlate with hPL concentrations in either group separately or when all subjects were considered together. These data do not support the hypothesis that maternal IGF-I secretion is an hPL-dependent process.",

author = "Kazer, {R. R.} and Cheng, {E. R.} and Unterman, {T. G.} and Glick, {R. P.}",

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T1 - Maternal plasma concentrations on insulin-like growth factor-I (IGF-I) and human placental lactogen (hPL) in twin pregnancies

AU - Kazer, R. R.

AU - Cheng, E. R.

AU - Unterman, T. G.

AU - Glick, R. P.

PY - 1991

Y1 - 1991

N2 - Maternal plasma IGF-I and hPL concentrations were examined in 10 singleton pregnancies and in 11 twin gestations near term. hPL concentrations were higher in the twin pregnancies (14.4 ± 2.4 μg/l vs 6.9 ± 0.9 μg/l, P < 0.02). In contrast, plasma IGF-I concentrations were similar in the singleton and twin pregnancies (533 ± 45 μg/l vs 572 ± 60 μg/l, respectively). IGF-I concentrations failed to correlate with hPL concentrations in either group separately or when all subjects were considered together. These data do not support the hypothesis that maternal IGF-I secretion is an hPL-dependent process.

AB - Maternal plasma IGF-I and hPL concentrations were examined in 10 singleton pregnancies and in 11 twin gestations near term. hPL concentrations were higher in the twin pregnancies (14.4 ± 2.4 μg/l vs 6.9 ± 0.9 μg/l, P < 0.02). In contrast, plasma IGF-I concentrations were similar in the singleton and twin pregnancies (533 ± 45 μg/l vs 572 ± 60 μg/l, respectively). IGF-I concentrations failed to correlate with hPL concentrations in either group separately or when all subjects were considered together. These data do not support the hypothesis that maternal IGF-I secretion is an hPL-dependent process.

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Maternal plasma concentrations on insulin-like growth factor-I (IGF-I) and human placental lactogen (hPL) in twin pregnancies

Abstract

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