The maximal rate of early, global left ventricular diastolic filling at rest, expressed in end diastolic volumes/second, has been proved to be capable of discriminating between patients with coronary artery disease and normal subjects. It has been hypothesized that maximal diastolic filling would retain, or even increase, its discriminatory power when measured during exercise. However, during exercise this parameter might depend to some extent on the heart rate achieved by the subject during maximal exertion. Since patients with coronary artery disease are often unable to achieve heart rates comparable to normal subjects at exercise, the apparent power of this parameter to achieve discrimination may be illusory. The results presented here are seen as suggesting that this is indeed the case and that the apparent power of maximal early filling rate to discriminate between patients with coronary artery diseases at exercise and normal subjects at exercise can be attributed almost entirely to differences in exercise heart rates between these groups.
|Original language||English (US)|
|Title of host publication||Computers in Cardiology|
|Editors||Kenneth L. Ripley|
|Number of pages||4|
|State||Published - Dec 1 1984|
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine