TY - JOUR
T1 - Meal timing relative to DLMO
T2 - Associations with BMI and body fat
AU - Culnan, Elizabeth
AU - Reid, Kathryn J.
AU - Zee, Phyllis C.
AU - Crowley, Stephanie J.
AU - Baron, Kelly G.
N1 - Funding Information:
Research reported in this publication was supported in part by the National Institutes of Health's National Heart Lung and Blood Institute 1K23HL109110-01 (KGB), 1R01HL141706-01A1 (KGB) and the National Center for Advancing Translational Sciences , grant number UL1TR001422 . The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health .
Publisher Copyright:
© 2021 National Sleep Foundation
PY - 2021
Y1 - 2021
N2 - Background: Timing of eating relative to the dim light melatonin onset (DLMO) may serve as a modifiable risk factor for adverse cardiometabolic outcomes. The primary aim of this study was to examine whether the timing of eating relative to DLMO is associated with body mass index (BMI), body fat, and diet in healthy adults without the confound of sleep deprivation. Methods: Healthy men and women (N = 97), ages 18-50, with a habitual sleep duration of ≥6.5 hours and ≤8.5 hours completed 7 days of actigraphy and daily sleep and food diaries. Participants underwent a dual-energy X-ray absorptiometry scan and blood draws to assess DLMO in the clinical research unit. Results: A shorter duration between DLMO and the average clock time of the last meal (last meal-DLMO) was related to a higher number of meals consumed, b = 0.25, SEb = 0.06, P< .001, longer feeding duration, b = 0.84, SEb = 0.06, P< .001, greater carbohydrate intake, b = 9.08, SEb = 3.55, P= .01, and greater sugar intake, b = 4.73, SEb = 1.83, P= .01. Last meal-DLMO was not associated with BMI in the full sample; however, among those with later DLMO (after 10:30 PM) last meal-DLMO was related to higher BMI, b = 0.92, SEb = 0.36, P= .02. Conclusion: These results suggest that timing of last meal relative to DLMO may serve as a marker of circadian misalignment and that eating the last meal closer to DLMO may negatively impact dietary habits.
AB - Background: Timing of eating relative to the dim light melatonin onset (DLMO) may serve as a modifiable risk factor for adverse cardiometabolic outcomes. The primary aim of this study was to examine whether the timing of eating relative to DLMO is associated with body mass index (BMI), body fat, and diet in healthy adults without the confound of sleep deprivation. Methods: Healthy men and women (N = 97), ages 18-50, with a habitual sleep duration of ≥6.5 hours and ≤8.5 hours completed 7 days of actigraphy and daily sleep and food diaries. Participants underwent a dual-energy X-ray absorptiometry scan and blood draws to assess DLMO in the clinical research unit. Results: A shorter duration between DLMO and the average clock time of the last meal (last meal-DLMO) was related to a higher number of meals consumed, b = 0.25, SEb = 0.06, P< .001, longer feeding duration, b = 0.84, SEb = 0.06, P< .001, greater carbohydrate intake, b = 9.08, SEb = 3.55, P= .01, and greater sugar intake, b = 4.73, SEb = 1.83, P= .01. Last meal-DLMO was not associated with BMI in the full sample; however, among those with later DLMO (after 10:30 PM) last meal-DLMO was related to higher BMI, b = 0.92, SEb = 0.36, P= .02. Conclusion: These results suggest that timing of last meal relative to DLMO may serve as a marker of circadian misalignment and that eating the last meal closer to DLMO may negatively impact dietary habits.
KW - Body composition
KW - Diet
KW - Melatonin
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U2 - 10.1016/j.sleh.2021.01.001
DO - 10.1016/j.sleh.2021.01.001
M3 - Article
C2 - 33610479
AN - SCOPUS:85101136008
JO - Sleep Health
JF - Sleep Health
SN - 2352-7218
ER -