Measurement of blood pressure via a skin-mounted, non-invasive pressure sensor

Shupeng Li, Yoonseok Park, Haiwen Luan, Heling Wang, Kyeongha Kwon, John A Rogers*, Yonggang Huang

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Traditional methods to measure blood pressure are intermittent and may fail to detect the critical blood pressure fluctuations. Continuous blood pressure monitoring offers important clinical value in predicting cardiovascular diseases. Invasive (i.e., artery cannulation) and noninvasive approaches (e.g., volume clamping, pressure sensor, ultrasound, and optical methods) have limitations that prevent their generalized use outside of controlled settings, and few account properly for changes in the properties of the arteries (e.g., after drug administration, aging). This article proposes a method that combines a skin-interfaced pressure sensor with a sensor of pulse wave velocity, to continuously, noninvasively, and accurately measure the blood pressure, in ways that eliminate drifts and other artifacts that can prevent accurate, longitudinal monitoring. A scaling law is established to show that, for a linearly proportional relationship between the blood pressure and sensor pressure, the coefficient of proportionality depends on the elastic moduli Eartery and Etissue of the artery and tissue, respectively, and the artery thickness hartery and radius Rartery via a single, dimensionless combination, Earteryhartery/(EtissueRartery), i.e., the normalized artery stiffness. This scheme determines the blood pressure in a manner that explicitly accounts for changes in the artery elastic modulus and thickness (e.g., due to the administration of drugs, aging).

Original languageEnglish (US)
Article number101008
JournalJournal of Applied Mechanics, Transactions ASME
Volume88
Issue number10
DOIs
StatePublished - Oct 2021

Keywords

  • Blood pressure
  • Pressure sensor
  • Pulse wave velocity
  • Scaling law

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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