Abstract
A stable isotope LC-MS procedure developed to determine the concentration of Mefox in human plasma while monitoring 5-methyltetrahydrofolic acid monoglutamate (5-MTHFA) using an alternate LC-MS method was discussed. Twenty-three plasma samples from smokers and nonsmokers drawn prior to 1995 (before folic acid fortification of foods) were analyzed for 5-MTHFA and Mefox. MRM was used to find Mefox to be present in only one of the plasmas analyzed at a concentration of 23.7 ng/ml. The range for 5-MTHFA was found to be 1.1 to 13.6 ng/ml with a mean of 3.5 ng/ml.
| Original language | English (US) |
|---|---|
| Title of host publication | Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics |
| Pages | 551-552 |
| Number of pages | 2 |
| State | Published - Dec 1 2002 |
| Event | Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics - Orlando, FL, United States Duration: Jun 2 2002 → Jun 6 2002 |
Other
| Other | Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics |
|---|---|
| Country/Territory | United States |
| City | Orlando, FL |
| Period | 6/2/02 → 6/6/02 |
ASJC Scopus subject areas
- Spectroscopy