TY - JOUR
T1 - Measurement of ventricular torsion by two-dimensional ultrasound speckle tracking imaging
AU - Notomi, Yuichi
AU - Lysyansky, Peter
AU - Setser, Randolph M.
AU - Shiota, Takahiro
AU - Popović, Zoran B.
AU - Martin-Miklovic, Maureen G.
AU - Weaver, Joan A.
AU - Oryszak, Stephanie J.
AU - Greenberg, Neil L.
AU - White, Richard D.
AU - Thomas, James D.
N1 - Funding Information:
Dr. Notomi is funded through a postdoctoral fellowship grant of the Ohio Valley affiliate of the American Heart Association (0325237B) and the current study is a part of the grant. This study also was supported in part by the National Aeronautics and Space Administration (Houston, Texas, Grant NCC9-58) and the Department of Defense (Fort Dietrich, Maryland, USAMRMC Grant #02360007).
PY - 2005/6/21
Y1 - 2005/6/21
N2 - OBJECTIVES: We sought to examine the accuracy/consistency of a novel ultrasound speckle tracking imaging (STI) method for left ventricular torsion (LVtor) measurement in comparison with tagged magnetic resonance imaging (MRI) (a time-domain method similar to STI) and Doppler tissue imaging (DTI) (a velocity-based approach). BACKGROUND: Left ventricular torsion from helically oriented myofibers is a key parameter of cardiac performance but is difficult to measure. Ultrasound STI is potentially suitable for measurement of angular motion because of its angle-independence. METHODS: We acquired basal and apical short-axis left ventricular (LV) images in 15 patients to estimate LVtor by STI and compare it with tagged MRI and DTI. Left ventricular torsion was defined as the net difference of LV rotation at the basal and apical planes. For the STI analysis, we used high-frame (104 ± 12 frames/s) second harmonic two-dimensional images. RESULTS: Data on 13 of 15 patients were usable for STI analysis, and LVtor profile estimated by STI strongly correlated with those by tagged MRI (y = 0.95x + 0.19, r = 0.93, p < 0.0001, analyzed by repeated-measures regression models). The STI torsional velocity profile also correlated well with that by the DTI method (y = 0.79x + 2.4, r = 0.76, p < 0.0001, by repeated-measures regression models) with acceptable bias. CONCLUSIONS: The STI estimation of LVtor is concordant with those analyzed by tagged MRI (data derived from tissue displacement) and also showed good agreement with those by DTI (data derived from tissue velocity). Ultrasound STI is a promising new method to assess LV torsional deformation and may make the assessment more available in clinical and research cardiology.
AB - OBJECTIVES: We sought to examine the accuracy/consistency of a novel ultrasound speckle tracking imaging (STI) method for left ventricular torsion (LVtor) measurement in comparison with tagged magnetic resonance imaging (MRI) (a time-domain method similar to STI) and Doppler tissue imaging (DTI) (a velocity-based approach). BACKGROUND: Left ventricular torsion from helically oriented myofibers is a key parameter of cardiac performance but is difficult to measure. Ultrasound STI is potentially suitable for measurement of angular motion because of its angle-independence. METHODS: We acquired basal and apical short-axis left ventricular (LV) images in 15 patients to estimate LVtor by STI and compare it with tagged MRI and DTI. Left ventricular torsion was defined as the net difference of LV rotation at the basal and apical planes. For the STI analysis, we used high-frame (104 ± 12 frames/s) second harmonic two-dimensional images. RESULTS: Data on 13 of 15 patients were usable for STI analysis, and LVtor profile estimated by STI strongly correlated with those by tagged MRI (y = 0.95x + 0.19, r = 0.93, p < 0.0001, analyzed by repeated-measures regression models). The STI torsional velocity profile also correlated well with that by the DTI method (y = 0.79x + 2.4, r = 0.76, p < 0.0001, by repeated-measures regression models) with acceptable bias. CONCLUSIONS: The STI estimation of LVtor is concordant with those analyzed by tagged MRI (data derived from tissue displacement) and also showed good agreement with those by DTI (data derived from tissue velocity). Ultrasound STI is a promising new method to assess LV torsional deformation and may make the assessment more available in clinical and research cardiology.
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U2 - 10.1016/j.jacc.2005.02.082
DO - 10.1016/j.jacc.2005.02.082
M3 - Article
C2 - 15963406
AN - SCOPUS:20444454687
SN - 0735-1097
VL - 45
SP - 2034
EP - 2041
JO - Journal of the American College of Cardiology
JF - Journal of the American College of Cardiology
IS - 12
ER -