TY - GEN
T1 - Mechanical Characterization of Biofilms by Optical Coherence Elastography (OCE) Measurements of Elastic Waves
AU - Liou, Hong Cin
AU - Sabba, Fabrizio
AU - Wells, George
AU - Balogun, Oluwaseyi
N1 - Publisher Copyright:
© 2019 IEEE.
PY - 2019/10
Y1 - 2019/10
N2 - Biofilms are biological materials composed of microbial communities encased in a self-produced extracellular polymeric substance (EPS). The viscoelastic properties of biofilms are related to the cross-link density in the EPS and ultimately the cohesiveness of biofilms. Accurate measurement of biofilm viscoelastic properties at the mesoscale remains a challenge. Rheological measurements, although being more common, provide only global properties, do not permit in-situ characterization, and are not amenable to complex sample geometries. To address these challenges, our work seeks to develop a nondestructive framework for characterizing biofilm viscoelastic properties using elastic wave propagation measured by the optical coherence elastography technique. The framework holds great potential to elucidate spatially varying mechanical properties and their correlation with sample morphology and composition.
AB - Biofilms are biological materials composed of microbial communities encased in a self-produced extracellular polymeric substance (EPS). The viscoelastic properties of biofilms are related to the cross-link density in the EPS and ultimately the cohesiveness of biofilms. Accurate measurement of biofilm viscoelastic properties at the mesoscale remains a challenge. Rheological measurements, although being more common, provide only global properties, do not permit in-situ characterization, and are not amenable to complex sample geometries. To address these challenges, our work seeks to develop a nondestructive framework for characterizing biofilm viscoelastic properties using elastic wave propagation measured by the optical coherence elastography technique. The framework holds great potential to elucidate spatially varying mechanical properties and their correlation with sample morphology and composition.
KW - biofilm
KW - elastic wave propagation
KW - nondestructive viscoelastic characterization
KW - optical coherence elastography
UR - http://www.scopus.com/inward/record.url?scp=85077565886&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85077565886&partnerID=8YFLogxK
U2 - 10.1109/ULTSYM.2019.8925714
DO - 10.1109/ULTSYM.2019.8925714
M3 - Conference contribution
AN - SCOPUS:85077565886
T3 - IEEE International Ultrasonics Symposium, IUS
SP - 2194
EP - 2197
BT - 2019 IEEE International Ultrasonics Symposium, IUS 2019
PB - IEEE Computer Society
T2 - 2019 IEEE International Ultrasonics Symposium, IUS 2019
Y2 - 6 October 2019 through 9 October 2019
ER -