Mechanisms of hemostasis

Abraham Haimed, Rachel S. Bercovitz

Research output: Chapter in Book/Report/Conference proceedingChapter


Hemostasis is an elegant process that balances the opposing forces of coagulation and anticoagulation. The hemostatic system protects the vasculature from uncontrolled bleeding on the one hand and excessive clotting on the other. This complex physiologic process involves interactions between blood vessels, platelets, and coagulation proteins that build and then break down the stable clot made up of blood cells and a fibrin mesh. Hemostasis plays an important role in our day-to-day lives to prevent blood loss from the numerous times our blood vessel walls are damaged; additionally, it is crucial to prevent hemorrhage and massive blood loss during surgery.

Original languageEnglish (US)
Title of host publicationHemostasis Management of the Pediatric Surgical Patient
Number of pages19
ISBN (Electronic)9780323904599
ISBN (Print)9780323904605
StatePublished - Jan 1 2023


  • Anticoagulation
  • Coagulation
  • Hemostasis
  • Hemostasis mechanism
  • Surgery

ASJC Scopus subject areas

  • General Agricultural and Biological Sciences
  • General Biochemistry, Genetics and Molecular Biology


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