Mechanisms of immunotherapeutic intervention by anti-CD40L (CD154) antibody in an animal model of multiple sclerosis

Keyphrases

• Acute Disease 66%
• Anti-CD154 66%
• Anti-CD40L 100%
• Antibody Treatment 100%
• Autoimmune Disease 33%
• CD154 100%
• CD40 33%
• CD40 Ligand (CD40L) 33%
• CD40/CD154 66%
• Cell Manufacturing 33%
• Central Nervous System 100%
• Central Nervous System Inflammation 33%
• Central Nervous System Pathology 33%
• Clinical Disease 33%
• Clinical Disease Progression 33%
• Costimulatory Molecules 33%
• Delayed Hypersensitivity 33%
• Demyelinating Diseases 33%
• Disease Model 33%
• Disease Relapse 33%
• Effector Cells 33%
• Effector Function 33%
• Encephalitogenic T Cells 33%
• Epitope 33%
• Epitope Spreading 33%
• Experimental Autoimmune Encephalomyelitis 66%
• Immunotherapeutic Intervention 100%
• Immunotherapeutic Strategy 33%
• Infiltration 33%
• Interferon Production 33%
• Interleukin-10 33%
• Interleukin-2 33%
• Interleukin-4 (IL-4) 33%
• Interleukin-5 (IL-5) 33%
• Macrophages 66%
• Microglia 33%
• Multiple Sclerosis 100%
• Myelin 100%
• Remission 33%
• SJL Mice 33%
• Specific T Cells 33%
• System Migration 33%
• T Cell Proliferation 33%
• T Cells 33%
• T-cell Mediated 33%
• Th1 Cells 33%
• Th1 Differentiation 33%

Immunology and Microbiology

• CD154 100%
• CD40 Ligand 100%
• Central Nervous System 83%
• Clinically Isolated Syndrome 16%
• Delayed Hypersensitivity 16%
• Effector Cell 16%
• Epitope 33%
• Experimental Autoimmune Encephalomyelitis 33%
• Immunology 100%
• Interferon Production 16%
• Interleukin 10 16%
• Interleukin 2 16%
• Interleukin 4 16%
• Interleukin 5 16%
• Macrophage 33%
• Microglia 16%
• Multiple Sclerosis 100%
• Myelin 50%
• Swiss James Lambert Mouse 16%
• T Cell 50%
• T Cell Proliferation 16%
• T Cell-Mediated Autoimmune Disease 16%
• Th1 Cell 16%