Mechanisms of spinal pain: The dorsal root ganglion and its role as a mediator of low-back pain

James Neil Weinstein*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

99 Scopus citations

Abstract

The dorsal root ganglion as a mediator for low-back pain in an animal model was investigated. Low-frequency vibration, a known mechanical cause of low-back pain, was in-vestigated. Quantitative results suggest a significant re-duction effect on substance P, one of several neurotransmitters located in the dorsal root ganglion. The functional results of these changes are currently under in-vestigation.

Original languageEnglish (US)
Pages (from-to)999-1001
Number of pages3
JournalSpine
Volume11
Issue number10
StatePublished - Jan 1 1986

Keywords

  • Dorsal root ganglion
  • Low-back pain
  • Neurophysiology
  • Substance P
  • Vibration

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Clinical Neurology

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