Median cleft face syndrome: MR and CT data from 11 children

Thomas P. Naidich*, Robin E. Osborn, Bruce Bauer, Michelle J. Naidich

*Corresponding author for this work

Research output: Contribution to journalArticle

31 Scopus citations

Abstract

Examination (including CT and magnetic resonance studies) of 11 unrelated children with median cleft face syndrome revealed 6 (55%) with dense calcification of the falx and 5 (45%) with interhemispheric lipoma. Of the 11 children, 3 exhibited Sedano facies type A. 4 exhibited Sedano facies type B, and 4 exhibited Sedano facies type D. Type A patients had no calcification or lipoma. TWo of three type A patients were products of separate twin gestations, the only twins in the series. Type B patients had frequent falx calcification (three of four) and interhemispheric lipoma (two of four). Two of the four type B patients had concurrent Goldenhar syndrome, the only such patients in the series. Type D patients also had frequent falx calcification (three of four) and interhemispheric lipoma (three of four). Patients with median cleft face syndrome and Sedano facies type B or D should be examined radiologically for concurrent intracranial pathology.

Original languageEnglish (US)
Pages (from-to)57-64
Number of pages8
JournalJournal of Computer Assisted Tomography
Volume12
Issue number1
DOIs
StatePublished - Jan 1 1988

Keywords

  • Anomalies, congenital
  • Cleft, facial
  • Computed tomography
  • Face, abnormalities
  • Magnetic resonance imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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