Mediation of Social Determinants and Hypertension by Epigenetic Age in CARDIA

Mindy D. Szeto; Hongyan Ning; Havisha Pedamallu; Yinan Zheng; Lisa Schneper; Brian Joyce; Kyeezu Kim; Kiarri N. Kershaw; Orna Reges; Lifang Hou; Norrina B. Allen; Daniel A. Notterman; Donald M Lloyd-Jones

doi:10.1161/HYPERTENSIONAHA.124.24080

Mediation of Social Determinants and Hypertension by Epigenetic Age in CARDIA

Mindy D. Szeto^*, Hongyan Ning, Havisha Pedamallu, Yinan Zheng, Lisa Schneper, Brian Joyce, Kyeezu Kim, Kiarri N. Kershaw, Orna Reges, Lifang Hou, Norrina B. Allen, Daniel A. Notterman, Donald M Lloyd-Jones

^*Corresponding author for this work

Preventive Medicine

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Original language	English (US)
Pages (from-to)	e22-e24
Journal	Hypertension
Volume	82
Issue number	3
DOIs	https://doi.org/10.1161/HYPERTENSIONAHA.124.24080
State	Published - Mar 1 2025

Funding

The CARDIA study (Coronary Artery Risk Development in Young Adults) is supported by contracts 75N92023D00002, 75N92023D00003, 75N92023D00004, 75N92023D00005, and 75N92023D00006 from the National Heart, Lung, and Blood Institute (NHLBI). The DNA methylation laboratory work and analytic component were funded by the American Heart Association (17SFRN33700278 and 14SFRN20790000). M.D. Szeto was additionally supported by 1F31HL173991 from the NHLBI.

Keywords

DNA methylation
biomarkers
epigenomics
hypertension
mediation analysis
social determinants of health
socioeconomic disparities in health

ASJC Scopus subject areas

Internal Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1161/HYPERTENSIONAHA.124.24080

Cite this

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keywords = "DNA methylation, biomarkers, epigenomics, hypertension, mediation analysis, social determinants of health, socioeconomic disparities in health",

author = "Szeto, {Mindy D.} and Hongyan Ning and Havisha Pedamallu and Yinan Zheng and Lisa Schneper and Brian Joyce and Kyeezu Kim and Kershaw, {Kiarri N.} and Orna Reges and Lifang Hou and Allen, {Norrina B.} and Notterman, {Daniel A.} and Lloyd-Jones, {Donald M}",

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T1 - Mediation of Social Determinants and Hypertension by Epigenetic Age in CARDIA

AU - Szeto, Mindy D.

AU - Ning, Hongyan

AU - Pedamallu, Havisha

AU - Zheng, Yinan

AU - Schneper, Lisa

AU - Joyce, Brian

AU - Kim, Kyeezu

AU - Kershaw, Kiarri N.

AU - Reges, Orna

AU - Hou, Lifang

AU - Allen, Norrina B.

AU - Notterman, Daniel A.

AU - Lloyd-Jones, Donald M

PY - 2025/3/1

Y1 - 2025/3/1

KW - DNA methylation

KW - biomarkers

KW - epigenomics

KW - hypertension

KW - mediation analysis

KW - social determinants of health

KW - socioeconomic disparities in health

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Mediation of Social Determinants and Hypertension by Epigenetic Age in CARDIA

Funding

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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