Medical comorbidities in disorders of consciousness patients and their association with functional outcomes

Shanti Ganesh, Ann Guernon, Laura Chalcraft, Brett Harton, Bridget Smith, Theresa Louise-Bender Pape*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

37 Scopus citations

Abstract

Objective: To identify, for patients in states of seriously impaired consciousness, comorbid conditions present during inpatient rehabilitation and their association with function at 1 year. Design: Abstracted data from a prospective cross-sectional observational study with data collection occurring January 1996 through December 2007. Setting: Four inpatient rehabilitation facilities in metropolitan areas. Participants: The study sample of 68 participants is abstracted from a database of 157 patients remaining in states of seriously impaired consciousness for at least 28 days. Interventions: Not applicable. Main Outcome Measure: One-year cognitive, motor, and total FIM score. Results: The most common medical complications during inpatient rehabilitation for the study sample are active seizures (46%), spasticity (57%), urinary tract infections (47%), and hydrocephalus with and without shunt (38%). Presence of ≥3 medical complications during inpatient rehabilitation, controlling for injury severity, is significantly (P<.05) associated with poorer total FIM and FIM motor scores 1 year after injury. The presence of hydrocephalus with and without shunt (r=-.20, -.21, -.18; P ≤.15), active seizures (r=-.31, -.22, -.42), spasticity (r=-.38, -.28, -.40), and urinary tract infections (r=-.25, -.24, -.26) were significantly (P<.10) associated with total FIM, FIM cognitive, and FIM motor scores, respectively. Conclusions: Reported findings indicate that persons in states of seriously impaired consciousness with higher numbers of medical complications during inpatient rehabilitation are more likely to have lower functional levels 1-year postinjury. The findings indicate that persons with ≥3 medical complications during inpatient rehabilitation are at a higher risk for poorer functional outcomes at 1 year. It is, therefore, prudent to evaluate these patients for indications of these complications during inpatient rehabilitation.

Original languageEnglish (US)
Pages (from-to)1899-1907.e3
JournalArchives of physical medicine and rehabilitation
Volume94
Issue number10
DOIs
StatePublished - Oct 2013

Keywords

  • Brain injuries
  • Comorbidity
  • Consciousness disorders
  • Rehabilitation

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation

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