Medical management of prolactin-secreting pituitary adenomas

Mark E Molitch*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

95 Scopus citations

Abstract

Prolactinomas are a common cause of reproductive/sexual dysfunction. Once other causes of hyperprolactinemia have been excluded with a careful history and physical examination, routine chemistries, a pregnancy test and a TSH, imaging with MRI or CT will delineate the size and extent of the tumor. Medical therapy is the initial treatment of choice. When infertility is the primary indication for treatment, bromocriptine use has an extensive safety experience and is preferred. However, for other indications, cabergoline appears to be more efficacious and better tolerated. Transsphenoidal surgery remains an option, especially for patients with microadenomas, when medical therapy is ineffective.

Original languageEnglish (US)
Pages (from-to)55-65
Number of pages11
JournalPituitary
Volume5
Issue number2
DOIs
StatePublished - Dec 1 2002

Keywords

  • Bromocriptine
  • Cabergoline
  • Pituitary tumor
  • Prolactin
  • Prolactinoma

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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