TY - CHAP
T1 - Melanoma
T2 - Clinical presentations
AU - Kibbi, Nour
AU - Kluger, Harriet
AU - Choi, Jennifer Nam
N1 - Publisher Copyright:
© Springer International Publishing Switzerland 2016.
PY - 2016
Y1 - 2016
N2 - The malignant cell in melanoma is the melanocyte. Because melanocytes are located in the basal layer of the epidermis, melanoma is most commonly seen on the skin. However, melanoma can also arise on mucosal surfaces such as the oral cavity, the upper gastrointestinal mucosa, the genital mucosa, as well as the uveal tract of the eye and leptomeninges. Melanomas tend to be pigmented but can also present as pink or red lesions. They can mimic benign or other malignant skin lesions. This chapter presents the spectrum of typical and less typical presentations of melanoma, as well as patterns of spread. It is divided into (1) cutaneous lesions; (2) patterns of regional spread, (3) non-cutaneous lesions; and (4) distant metastases.
AB - The malignant cell in melanoma is the melanocyte. Because melanocytes are located in the basal layer of the epidermis, melanoma is most commonly seen on the skin. However, melanoma can also arise on mucosal surfaces such as the oral cavity, the upper gastrointestinal mucosa, the genital mucosa, as well as the uveal tract of the eye and leptomeninges. Melanomas tend to be pigmented but can also present as pink or red lesions. They can mimic benign or other malignant skin lesions. This chapter presents the spectrum of typical and less typical presentations of melanoma, as well as patterns of spread. It is divided into (1) cutaneous lesions; (2) patterns of regional spread, (3) non-cutaneous lesions; and (4) distant metastases.
KW - Atypical pigmented cutaneous lesions
KW - Melanoma of unknown primary site
KW - Non-cutaneous melanoma
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U2 - 10.1007/978-3-319-22539-5_4
DO - 10.1007/978-3-319-22539-5_4
M3 - Chapter
C2 - 26601860
AN - SCOPUS:84948807274
T3 - Cancer Treatment and Research
SP - 107
EP - 129
BT - Cancer Treatment and Research
PB - Kluwer Academic Publishers
ER -