Melatonin-Induced Inhibition of Testicular Function in Adult Golden Hamsters

Fred W. Turek*, Claude Desjardins, Michael Menaker

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

30 Scopus citations

Abstract

Melatonin (12-100 μg/day) administered via subcutaneous Silastic implants prevented or suppressed light-induced testicular recrudescence in adult golden hamsters. In addition, melatonin (150 μg/day) induced marked testicular regression in sexually mature hamsters maintained on photostimulatory long days. These results clearly establish that exogenous melatonin can inhibit gonadal function in adult male hamsters. The authors express their appreciation to Donald W. Carroll for expert assistance provided throughout this study.

Original languageEnglish (US)
Pages (from-to)502-506
Number of pages5
JournalProceedings of the Society for Experimental Biology and Medicine
Volume151
Issue number3
DOIs
StatePublished - Mar 1976

Funding

This investigation was supported by USPHS Program Project Grant No. HD-03803, and Research Training Grant No. HD-00268 from the National Institute of Child Health and Human Development. 2

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology

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