Membrane trafficking, organelle transport, and the cytoskeleton

Stephen L. Rogers*, Vladimir I. Gelfand

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

145 Scopus citations


Cytoskeleton-associated motor proteins typically drive organelle movements in eukaryotic cells in a manner that is tightly regulated, both spatially and temporally. In the past year, a novel organelle transport mechanism utilizing actin polymerization was described. Important advances were also made in the assignment of functions to several new motors and in our understanding of how motor proteins are regulated during organelle transport. In addition, insights were gained into how and why organelles are transported cooperatively along the microtubule and actin cytoskeletons, and into the importance of motor-mediated transport in the organization of the cytoskeleton itself.

Original languageEnglish (US)
Pages (from-to)57-62
Number of pages6
JournalCurrent Opinion in Cell Biology
Issue number1
StatePublished - Feb 1 2000

ASJC Scopus subject areas

  • Cell Biology

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