Memory performance is related to language dominance as determined by the intracarotid amobarbital procedure

S. Kovac; G. Möddel; J. Reinholz; A. V. Alexopoulos; T. Syed; S. U. Schuele; T. Lineweaver; T. Loddenkemper

doi:10.1016/j.yebeh.2009.07.020

Memory performance is related to language dominance as determined by the intracarotid amobarbital procedure

S. Kovac^*, G. Möddel, J. Reinholz, A. V. Alexopoulos, T. Syed, S. U. Schuele, T. Lineweaver, T. Loddenkemper

^*Corresponding author for this work

Neurology

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Objective: The goal of this study was to explore the relationship between language and memory lateralization in patients with epilepsy undergoing the intracarotid amobarbital procedure. Methods: In 386 patients, language lateralization and memory lateralization as determined by laterality index (LI) were correlated with each other. Results: Language lateralization and memory lateralization were positively correlated (r = 0.34, P < 0.01). Correlations differed depending on the presence and type of lesion (χ² = 7.98, P < 0.05). LIs correlated significantly higher (z = 2.82, P < 0.05) in patients with cortical dysplasia (n = 41, r = 0.61, P < 0.01) compared with the group without lesions (n = 90, r = 0.16, P > 0.05), with patients with hippocampal sclerosis falling between these two groups. Both memory (P < 0.01) and language (P < 0.01) LIs were higher in right- compared with left-sided lesions. Conclusion: Correlation of language and memory is more pronounced in patients with structural lesions as compared with patients without lesions on MRI.

Original language	English (US)
Pages (from-to)	145-149
Number of pages	5
Journal	Epilepsy and Behavior
Volume	16
Issue number	1
DOIs	https://doi.org/10.1016/j.yebeh.2009.07.020
State	Published - Sep 2009

Keywords

Epilepsy
Language
Memory
Wada test

ASJC Scopus subject areas

Clinical Neurology
Neurology
Behavioral Neuroscience

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10.1016/j.yebeh.2009.07.020

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@article{56301fa0be414be39a6fec9d0ff59b13,

title = "Memory performance is related to language dominance as determined by the intracarotid amobarbital procedure",

abstract = "Objective: The goal of this study was to explore the relationship between language and memory lateralization in patients with epilepsy undergoing the intracarotid amobarbital procedure. Methods: In 386 patients, language lateralization and memory lateralization as determined by laterality index (LI) were correlated with each other. Results: Language lateralization and memory lateralization were positively correlated (r = 0.34, P < 0.01). Correlations differed depending on the presence and type of lesion (χ2 = 7.98, P < 0.05). LIs correlated significantly higher (z = 2.82, P < 0.05) in patients with cortical dysplasia (n = 41, r = 0.61, P < 0.01) compared with the group without lesions (n = 90, r = 0.16, P > 0.05), with patients with hippocampal sclerosis falling between these two groups. Both memory (P < 0.01) and language (P < 0.01) LIs were higher in right- compared with left-sided lesions. Conclusion: Correlation of language and memory is more pronounced in patients with structural lesions as compared with patients without lesions on MRI.",

keywords = "Epilepsy, Language, Memory, Wada test",

author = "S. Kovac and G. M{\"o}ddel and J. Reinholz and Alexopoulos, {A. V.} and T. Syed and Schuele, {S. U.} and T. Lineweaver and T. Loddenkemper",

note = "Funding Information: Author S.K. was supported by grant Felgenhauer and short-term grant NeuroNRW, Germany. Author G.M. was supported by IMF 620202, Innovative Medizinische Forschung, University of M{\"u}nster, Germany. ",

year = "2009",

month = sep,

doi = "10.1016/j.yebeh.2009.07.020",

language = "English (US)",

volume = "16",

pages = "145--149",

journal = "Epilepsy and Behavior",

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T1 - Memory performance is related to language dominance as determined by the intracarotid amobarbital procedure

AU - Kovac, S.

AU - Möddel, G.

AU - Reinholz, J.

AU - Alexopoulos, A. V.

AU - Syed, T.

AU - Schuele, S. U.

AU - Lineweaver, T.

AU - Loddenkemper, T.

N1 - Funding Information: Author S.K. was supported by grant Felgenhauer and short-term grant NeuroNRW, Germany. Author G.M. was supported by IMF 620202, Innovative Medizinische Forschung, University of Münster, Germany.

PY - 2009/9

Y1 - 2009/9

N2 - Objective: The goal of this study was to explore the relationship between language and memory lateralization in patients with epilepsy undergoing the intracarotid amobarbital procedure. Methods: In 386 patients, language lateralization and memory lateralization as determined by laterality index (LI) were correlated with each other. Results: Language lateralization and memory lateralization were positively correlated (r = 0.34, P < 0.01). Correlations differed depending on the presence and type of lesion (χ2 = 7.98, P < 0.05). LIs correlated significantly higher (z = 2.82, P < 0.05) in patients with cortical dysplasia (n = 41, r = 0.61, P < 0.01) compared with the group without lesions (n = 90, r = 0.16, P > 0.05), with patients with hippocampal sclerosis falling between these two groups. Both memory (P < 0.01) and language (P < 0.01) LIs were higher in right- compared with left-sided lesions. Conclusion: Correlation of language and memory is more pronounced in patients with structural lesions as compared with patients without lesions on MRI.

AB - Objective: The goal of this study was to explore the relationship between language and memory lateralization in patients with epilepsy undergoing the intracarotid amobarbital procedure. Methods: In 386 patients, language lateralization and memory lateralization as determined by laterality index (LI) were correlated with each other. Results: Language lateralization and memory lateralization were positively correlated (r = 0.34, P < 0.01). Correlations differed depending on the presence and type of lesion (χ2 = 7.98, P < 0.05). LIs correlated significantly higher (z = 2.82, P < 0.05) in patients with cortical dysplasia (n = 41, r = 0.61, P < 0.01) compared with the group without lesions (n = 90, r = 0.16, P > 0.05), with patients with hippocampal sclerosis falling between these two groups. Both memory (P < 0.01) and language (P < 0.01) LIs were higher in right- compared with left-sided lesions. Conclusion: Correlation of language and memory is more pronounced in patients with structural lesions as compared with patients without lesions on MRI.

KW - Epilepsy

KW - Language

KW - Memory

KW - Wada test

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Memory performance is related to language dominance as determined by the intracarotid amobarbital procedure

Abstract

Keywords

ASJC Scopus subject areas

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