Memory performance is related to language dominance as determined by the intracarotid amobarbital procedure

S. Kovac*, G. Möddel, J. Reinholz, A. V. Alexopoulos, T. Syed, S. U. Schuele, T. Lineweaver, T. Loddenkemper

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Objective: The goal of this study was to explore the relationship between language and memory lateralization in patients with epilepsy undergoing the intracarotid amobarbital procedure. Methods: In 386 patients, language lateralization and memory lateralization as determined by laterality index (LI) were correlated with each other. Results: Language lateralization and memory lateralization were positively correlated (r = 0.34, P < 0.01). Correlations differed depending on the presence and type of lesion (χ2 = 7.98, P < 0.05). LIs correlated significantly higher (z = 2.82, P < 0.05) in patients with cortical dysplasia (n = 41, r = 0.61, P < 0.01) compared with the group without lesions (n = 90, r = 0.16, P > 0.05), with patients with hippocampal sclerosis falling between these two groups. Both memory (P < 0.01) and language (P < 0.01) LIs were higher in right- compared with left-sided lesions. Conclusion: Correlation of language and memory is more pronounced in patients with structural lesions as compared with patients without lesions on MRI.

Original languageEnglish (US)
Pages (from-to)145-149
Number of pages5
JournalEpilepsy and Behavior
Volume16
Issue number1
DOIs
StatePublished - Sep 2009

Keywords

  • Epilepsy
  • Language
  • Memory
  • Wada test

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Behavioral Neuroscience

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