Mental Health, Sleep and Physical Function in Treatment Seeking Women with Urinary Incontinence

LURN

Research output: Contribution to journalArticle

Abstract

Purpose: We examined how mental health measures, sleep and physical function are associated with the presence and type of urinary incontinence and severity in women seeking treatment for lower urinary tract symptoms. Materials and Methods: This baseline cross-sectional analysis was performed in treatment seeking women with lower urinary tract symptoms. All participants completed the LUTS (Lower Urinary Tract Symptoms) Tool (Pfizer, New York, New York), which was used to classify women based on urinary incontinence symptoms and measure severity. The PROMIS (Patient-Reported Outcomes Measurement Information System) questionnaire for depression, anxiety, sleep disturbance and physical function, the PSS (Perceived Stress Scale) and the IPAQ-SF (International Physical Activity Questionnaire Short Form) were administered. Multivariable regression modeling was done to assess associations with urinary symptom presence, type and severity. Results: We studied 510 women with a mean ± SD age of 56 ± 14 years. Of the women 82% were Caucasian, 47% were obese and 14% reported diabetes. Urinary incontinence was reported by 420 women (82.4%), including stress urinary incontinence in 70, urgency urinary incontinence in 85, mixed urinary incontinence in 240 and other urinary incontinence in 25. On adjusted analyses there was no difference in any mental health, sleep or physical function measure based on the presence vs the absence of urinary incontinence. Among women with urinary incontinence PROMIS anxiety and sleep disturbance scores were higher in those with mixed urinary incontinence than stress urinary incontinence. Increasing urinary incontinence severity was associated with higher PROMIS depression and anxiety scores, and higher PSS scores. However, higher urinary incontinence severity was not associated with a difference in sleep or physical function. Conclusions: Among treatment seeking women with lower urinary tract symptoms, increasing urinary incontinence severity rather than the presence or type of urinary incontinence was associated with increased depression, anxiety and stress.

Original languageEnglish (US)
Pages (from-to)848-855
Number of pages8
JournalJournal of Urology
Volume200
Issue number4
DOIs
StatePublished - Oct 1 2018

Fingerprint

Urinary Incontinence
Mental Health
Sleep
Lower Urinary Tract Symptoms
Therapeutics
Anxiety
Information Systems
Stress Urinary Incontinence
Depression
Cross-Sectional Studies

Keywords

  • anxiety
  • depression
  • patient reported outcome measures
  • urinary bladder
  • urinary incontinence

ASJC Scopus subject areas

  • Urology

Cite this

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title = "Mental Health, Sleep and Physical Function in Treatment Seeking Women with Urinary Incontinence",
abstract = "Purpose: We examined how mental health measures, sleep and physical function are associated with the presence and type of urinary incontinence and severity in women seeking treatment for lower urinary tract symptoms. Materials and Methods: This baseline cross-sectional analysis was performed in treatment seeking women with lower urinary tract symptoms. All participants completed the LUTS (Lower Urinary Tract Symptoms) Tool (Pfizer, New York, New York), which was used to classify women based on urinary incontinence symptoms and measure severity. The PROMIS (Patient-Reported Outcomes Measurement Information System) questionnaire for depression, anxiety, sleep disturbance and physical function, the PSS (Perceived Stress Scale) and the IPAQ-SF (International Physical Activity Questionnaire Short Form) were administered. Multivariable regression modeling was done to assess associations with urinary symptom presence, type and severity. Results: We studied 510 women with a mean ± SD age of 56 ± 14 years. Of the women 82{\%} were Caucasian, 47{\%} were obese and 14{\%} reported diabetes. Urinary incontinence was reported by 420 women (82.4{\%}), including stress urinary incontinence in 70, urgency urinary incontinence in 85, mixed urinary incontinence in 240 and other urinary incontinence in 25. On adjusted analyses there was no difference in any mental health, sleep or physical function measure based on the presence vs the absence of urinary incontinence. Among women with urinary incontinence PROMIS anxiety and sleep disturbance scores were higher in those with mixed urinary incontinence than stress urinary incontinence. Increasing urinary incontinence severity was associated with higher PROMIS depression and anxiety scores, and higher PSS scores. However, higher urinary incontinence severity was not associated with a difference in sleep or physical function. Conclusions: Among treatment seeking women with lower urinary tract symptoms, increasing urinary incontinence severity rather than the presence or type of urinary incontinence was associated with increased depression, anxiety and stress.",
keywords = "anxiety, depression, patient reported outcome measures, urinary bladder, urinary incontinence",
author = "LURN and Siddiqui, {Nazema Y.} and Wiseman, {Jonathan B.} and David Cella and Bradley, {Catherine S.} and Lai, {H. Henry} and Helmuth, {Margaret E.} and Smith, {Abigail R.} and Griffith, {James W} and Amundsen, {Cindy L.} and Kenton, {Kimberly Sue} and Clemens, {J. Quentin} and Kreder, {Karl J.} and Merion, {Robert M.} and Ziya Kirkali and Kusek, {John W.} and Cameron, {Anne P.}",
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language = "English (US)",
volume = "200",
pages = "848--855",
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Mental Health, Sleep and Physical Function in Treatment Seeking Women with Urinary Incontinence. / LURN.

In: Journal of Urology, Vol. 200, No. 4, 01.10.2018, p. 848-855.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Mental Health, Sleep and Physical Function in Treatment Seeking Women with Urinary Incontinence

AU - LURN

AU - Siddiqui, Nazema Y.

AU - Wiseman, Jonathan B.

AU - Cella, David

AU - Bradley, Catherine S.

AU - Lai, H. Henry

AU - Helmuth, Margaret E.

AU - Smith, Abigail R.

AU - Griffith, James W

AU - Amundsen, Cindy L.

AU - Kenton, Kimberly Sue

AU - Clemens, J. Quentin

AU - Kreder, Karl J.

AU - Merion, Robert M.

AU - Kirkali, Ziya

AU - Kusek, John W.

AU - Cameron, Anne P.

PY - 2018/10/1

Y1 - 2018/10/1

N2 - Purpose: We examined how mental health measures, sleep and physical function are associated with the presence and type of urinary incontinence and severity in women seeking treatment for lower urinary tract symptoms. Materials and Methods: This baseline cross-sectional analysis was performed in treatment seeking women with lower urinary tract symptoms. All participants completed the LUTS (Lower Urinary Tract Symptoms) Tool (Pfizer, New York, New York), which was used to classify women based on urinary incontinence symptoms and measure severity. The PROMIS (Patient-Reported Outcomes Measurement Information System) questionnaire for depression, anxiety, sleep disturbance and physical function, the PSS (Perceived Stress Scale) and the IPAQ-SF (International Physical Activity Questionnaire Short Form) were administered. Multivariable regression modeling was done to assess associations with urinary symptom presence, type and severity. Results: We studied 510 women with a mean ± SD age of 56 ± 14 years. Of the women 82% were Caucasian, 47% were obese and 14% reported diabetes. Urinary incontinence was reported by 420 women (82.4%), including stress urinary incontinence in 70, urgency urinary incontinence in 85, mixed urinary incontinence in 240 and other urinary incontinence in 25. On adjusted analyses there was no difference in any mental health, sleep or physical function measure based on the presence vs the absence of urinary incontinence. Among women with urinary incontinence PROMIS anxiety and sleep disturbance scores were higher in those with mixed urinary incontinence than stress urinary incontinence. Increasing urinary incontinence severity was associated with higher PROMIS depression and anxiety scores, and higher PSS scores. However, higher urinary incontinence severity was not associated with a difference in sleep or physical function. Conclusions: Among treatment seeking women with lower urinary tract symptoms, increasing urinary incontinence severity rather than the presence or type of urinary incontinence was associated with increased depression, anxiety and stress.

AB - Purpose: We examined how mental health measures, sleep and physical function are associated with the presence and type of urinary incontinence and severity in women seeking treatment for lower urinary tract symptoms. Materials and Methods: This baseline cross-sectional analysis was performed in treatment seeking women with lower urinary tract symptoms. All participants completed the LUTS (Lower Urinary Tract Symptoms) Tool (Pfizer, New York, New York), which was used to classify women based on urinary incontinence symptoms and measure severity. The PROMIS (Patient-Reported Outcomes Measurement Information System) questionnaire for depression, anxiety, sleep disturbance and physical function, the PSS (Perceived Stress Scale) and the IPAQ-SF (International Physical Activity Questionnaire Short Form) were administered. Multivariable regression modeling was done to assess associations with urinary symptom presence, type and severity. Results: We studied 510 women with a mean ± SD age of 56 ± 14 years. Of the women 82% were Caucasian, 47% were obese and 14% reported diabetes. Urinary incontinence was reported by 420 women (82.4%), including stress urinary incontinence in 70, urgency urinary incontinence in 85, mixed urinary incontinence in 240 and other urinary incontinence in 25. On adjusted analyses there was no difference in any mental health, sleep or physical function measure based on the presence vs the absence of urinary incontinence. Among women with urinary incontinence PROMIS anxiety and sleep disturbance scores were higher in those with mixed urinary incontinence than stress urinary incontinence. Increasing urinary incontinence severity was associated with higher PROMIS depression and anxiety scores, and higher PSS scores. However, higher urinary incontinence severity was not associated with a difference in sleep or physical function. Conclusions: Among treatment seeking women with lower urinary tract symptoms, increasing urinary incontinence severity rather than the presence or type of urinary incontinence was associated with increased depression, anxiety and stress.

KW - anxiety

KW - depression

KW - patient reported outcome measures

KW - urinary bladder

KW - urinary incontinence

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