Mental Health Symptoms and Functional Impairment in Children With Atopic Dermatitis

Brian T. Cheng, Anna B. Fishbein, Jonathan Ian Silverberg

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


BACKGROUND: The impact of childhood atopic dermatitis (AD) on social and behavioral issues is not well understood. OBJECTIVE: This study sought to determine the prevalence and predictors of social and behavioral symptoms and functional impairment among US children with AD. METHODS: The 1996 to 2015 Medical Expenditure Panel Surveys were analyzed, including a representative, cross-sectional study of 2553 US children with AD. Behavioral and functional issues were examined using Columbia Impairment Scale (CIS) scores. RESULTS: Childhood AD was associated with behavioral and functional problems, particularly nervousness (odds ratio [OR], 1.18; 95% confidence interval [95% CI], 1.06-1.31), home behavior (OR, 1.18; 95% CI, 1.06-1.32), staying out of trouble (OR, 1.18; 95% confidence interval, 1.06-1.31), and relationships with other kids (OR, 1.17; 95% CI, 1.05-1.31) and with siblings (OR, 1.14; 95% CI, 1.02-1.28). Higher CIS scores were present in children with AD versus without AD (adjusted β, 0.62; 95% CI, 0.22-1.02) and with psoriasis (adjusted β, 0.86; 95% CI, 0.22-1.49). Among children with AD, higher CIS scores were notably associated with male sex, older age, lower household income, public insurance, and comorbid depression and anxiety. CONCLUSIONS: AD was associated with behavioral and functional impairment, similar to psoriasis and other common chronic conditions. There are significant sociodemographic differences in CIS scores.

Original languageEnglish (US)
Pages (from-to)353-361
Number of pages9
JournalDermatitis : contact, atopic, occupational, drug
Issue number5
StatePublished - Sep 1 2021

ASJC Scopus subject areas

  • Immunology and Allergy
  • Dermatology


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