Merkel cell carcinoma metastatic to the small bowel mesentery

Kristina A. Matkowskyj, Ava Hosseini, John G. Linn, Guang Yu Yang, Timothy M. Kuzel, Jeffrey D. Wayne

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Merkel cell carcinoma (MCC) is an uncommon cutaneous malignant tumor that presents as a rapidly growing skin nodule on sun-exposed areas of the body. MCC is aggressive with regional nodal and distant metastases to the skin, lung, and bones. There have been no reports of metastatic MCC to the mesentery and 6 reports describing metastasis to the small intestine. We present a case of metastatic MCC to the mesentery with infiltration to the small bowel, 8 years after original tumor resection. This is the 5th metastasis and it encased the small bowel resulting in a hair-pin loop contributing to the unusual clinical presentation. Although MCC metastatic to the bowel is uncommon, it is not rare. It is important to recognize the unusual manifestations of this disease as they are becoming more common in the future. Routine radiologic surveillance and thorough review of systems are important to patient follow-up.

Original languageEnglish (US)
Pages (from-to)4-6
Number of pages3
JournalRare Tumors
Issue number1
StatePublished - 2011


  • Cytokeratin 20
  • Merkel cell carcinoma
  • Mesentery
  • Metastasis
  • Small intestine

ASJC Scopus subject areas

  • Histology
  • Oncology

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