Mesostructured multifunctional nanoparticles for imaging and drug delivery

Monty Liong, Sarah Angelos, Eunshil Choi, Kaushik Patel, J. Fraser Stoddart, Jeffrey I. Zink

Research output: Contribution to journalArticle

183 Scopus citations

Abstract

Mesostructured silica particles (∼100 nm diameter with ∼2 nm pores) prepared by surfactant-templated sol-gel techniques are versatile supports that can be easily derivatized with active molecules to create multifunctional materials. By deliberately placing active molecules in different regions of the mesostructure, fluorescent molecules, molecular machines, targeting ligands, and metal nanocrystals can be combined on a single particle. This review highlights the research in which multiple components are incorporated onto mesoporous silica for simultaneous imaging and delivery of molecules in biological applications.

Original languageEnglish (US)
Pages (from-to)6251-6257
Number of pages7
JournalJournal of Materials Chemistry
Volume19
Issue number35
DOIs
StatePublished - Sep 1 2009

ASJC Scopus subject areas

  • Chemistry(all)
  • Materials Chemistry

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