Metabolic Syndrome and Sleep

Only in the past few years have the modern-day epidemics of obesity and chronic sleep loss been linked with one another. Both controlled clinical studies and epidemiological studies have provided evidence that chronic partial sleep loss may lead to obesity and associated metabolic disorders. Emerging data from animal models for sleep loss, as well as for circadian dysregulation, are beginning to define at a mechanistic level how the sleep-wake, circadian clock, and energy balance systems are influencing one another at various levels of organization, both in the periphery and in the central nervous system.