Metabolism: How removal of damaged cells impacts energy availability in the retina

Connor Lantz; Edward B. Thorp

doi:10.1016/j.cub.2023.02.044

Metabolism: How removal of damaged cells impacts energy availability in the retina

Connor Lantz, Edward B. Thorp

Pathology

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

Once thought to be a quiescent process, elimination of damaged cells by professional phagocytes is now understood to modulate metabolite availability within tissues. A new study reveals that the retinal pigment epithelium serves as a local source of insulin after engulfment of damaged photoreceptors.

Original language	English (US)
Pages (from-to)	R279-R282
Journal	Current Biology
Volume	33
Issue number	7
DOIs	https://doi.org/10.1016/j.cub.2023.02.044
State	Published - Apr 10 2023

ASJC Scopus subject areas

Neuroscience(all)
Biochemistry, Genetics and Molecular Biology(all)
Agricultural and Biological Sciences(all)

Access to Document

10.1016/j.cub.2023.02.044

Cite this

@article{72c730946fba46ec8888bdfce1ce507f,

title = "Metabolism: How removal of damaged cells impacts energy availability in the retina",

abstract = "Once thought to be a quiescent process, elimination of damaged cells by professional phagocytes is now understood to modulate metabolite availability within tissues. A new study reveals that the retinal pigment epithelium serves as a local source of insulin after engulfment of damaged photoreceptors.",

author = "Connor Lantz and Thorp, {Edward B.}",

note = "Funding Information: The authors declare no competing interests. Publisher Copyright: {\textcopyright} 2023 Elsevier Inc.",

year = "2023",

month = apr,

day = "10",

doi = "10.1016/j.cub.2023.02.044",

language = "English (US)",

volume = "33",

pages = "R279--R282",

journal = "Current Biology",

issn = "0960-9822",

publisher = "Cell Press",

number = "7",

}

TY - JOUR

T1 - Metabolism

T2 - How removal of damaged cells impacts energy availability in the retina

AU - Lantz, Connor

AU - Thorp, Edward B.

PY - 2023/4/10

Y1 - 2023/4/10

N2 - Once thought to be a quiescent process, elimination of damaged cells by professional phagocytes is now understood to modulate metabolite availability within tissues. A new study reveals that the retinal pigment epithelium serves as a local source of insulin after engulfment of damaged photoreceptors.

AB - Once thought to be a quiescent process, elimination of damaged cells by professional phagocytes is now understood to modulate metabolite availability within tissues. A new study reveals that the retinal pigment epithelium serves as a local source of insulin after engulfment of damaged photoreceptors.

UR - http://www.scopus.com/inward/record.url?scp=85151567457&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85151567457&partnerID=8YFLogxK

U2 - 10.1016/j.cub.2023.02.044

DO - 10.1016/j.cub.2023.02.044

M3 - Comment/debate

C2 - 37040713

AN - SCOPUS:85151567457

SN - 0960-9822

VL - 33

SP - R279-R282

JO - Current Biology

JF - Current Biology

IS - 7

ER -

Metabolism: How removal of damaged cells impacts energy availability in the retina

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this