Abstract
Metal complexes are gaining wider applications as enzyme inhibitors for disease treatments. Factors such as specificity, bioavailability, compensatory effects and complex stability are taken into account before such complexes function as therapeutic agents. The applications of metal complex enzyme inhibitors to normal and abnormal physiology, infections and toxicity are discussed.
Original language | English (US) |
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Pages (from-to) | 2711-2734 |
Number of pages | 24 |
Journal | Chemical Reviews |
Volume | 99 |
Issue number | 9 |
DOIs | |
State | Published - Sep 1999 |
ASJC Scopus subject areas
- General Chemistry