Metastatic dedifferentiated chordoma with elevated β-hCG: A case report

Hidayatullah G. Munshi, Sofia D. Merajver*, Riccardo Valdez, Laurence H. Baker, Kathleen A. Cooney

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Chordomas are relatively uncommon bone tumors, and fewer than 10% of cases are classified as dedifferentiated chordomas. These tumors tend to be more clinically aggressive than chordomas and have a higher incidence of early distant metastases. In this case report, we describe a 24-year-old man with dedifferentiated chordoma and multiple pulmonary metastases. Further laboratory analysis revealed an elevated serum β-human chorionic gonadotropin level. Unfortunately, the patient's clinical condition deteriorated rapidly and he died before receiving any treatment for his cancer. However, chemotherapy may play a useful role in the management of systemic disease in patients with dedifferentiated chordoma.

Original languageEnglish (US)
Pages (from-to)274-276
Number of pages3
JournalAmerican Journal of Clinical Oncology: Cancer Clinical Trials
Issue number3
StatePublished - Jun 18 2002


  • Chordoma
  • Dedifferentiated
  • β-hCG-radiation therapy

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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