Metastatic testicular choriocarcinoma and secondary hyperthyroidism: Case report and review of the literature

P. E. Gleason, D. S. Elliott, D. Zimmerman, W. A. Smithson, S. A. Kramer*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

We report on a 16-year-old boy with metastatic testicular choriocarcinoma, increased levels of human chorionic gonadotropin and profound hyperthyroidism bordering on thyroid storm. Hyperthyroidism was secondary to elevated human chorionic gonadotropin, with a thyroid-stimulating hormone effect. Management consisted of suppressive therapy for the symptoms of thyrotoxicosis until chemotherapy achieved control of the primary tumor and elevated levels of human chorionic gonadotropin. Review of the urological literature demonstrated a lack of recognition of this potentially serious paraneoplastic syndrome and its management.

Original languageEnglish (US)
Pages (from-to)1063-1064
Number of pages2
JournalJournal of Urology
Volume151
Issue number4
DOIs
StatePublished - Jan 1 1994

Keywords

  • choriocarcinoma
  • hyperthyroidism
  • testicular neoplasms

ASJC Scopus subject areas

  • Urology

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