Methodological Considerations in the Treatment of Fatigue

Lynne I. Wagner*, David Cella, Amy H. Peterman

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter


Due to recent medical advances, the life expectancy of people with chronic medical illness has been increasing. Fatigue is a symptom commonly associated with medical illness and has a high prevalence in palliative care settings. Fatigue is multidimensional in clinical expression and manifest in physical, emotional, and cognitive impairments. Fatigue is one of the most prevalent symptoms reported by patients with cancer, acquired immunodeficiency syndrome (AIDS), and multiple sclerosis. The presence of fatigue has been associated with functional limitations and impaired quality of life among chronically ill populations, including cancer and AIDS patients, and has been found to interfere with adherence to cancer treatment. This chapter holds that effective strategies for the clinical management of fatigue would reduce the overall symptom burden of many chronic illnesses.

Original languageEnglish (US)
Title of host publicationIssues in Palliative Care Research
PublisherOxford University Press
ISBN (Electronic)9780199999842
ISBN (Print)0195130650, 9780195130652
StatePublished - Nov 17 2011


  • AIDS
  • Cancer
  • Fatigue management
  • Life expectancy
  • Medical illness
  • Multiple sclerosis

ASJC Scopus subject areas

  • Nursing(all)


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