Abstract
Animal models of autism spectrum disorders (ASD) contribute to understanding of the role of genetics and the biological mechanisms underlying behavioral phenotypes and inform the development of potential treatments. Translational biomarkers are needed that can both validate these models and facilitate behavioral testing paradigms for ASD in humans. Automated video tracking of movement patterns and positions recorded from overhead cameras is routinely applied in behavioral paradigms designed to elicit core behavioral manifestations of ASD in rodent models. In humans, laboratory-based observations are a common semi-naturalistic context for assessing a variety of behaviors relevant to ASD such as social engagement, play, and attention. We present information learned and suggest guidelines for designing, recording, acquiring, and evaluating video tracking data of human movement patterns based on our experience in a multi-site video tracking study of children with ASD in the context of a parent-child, laboratory-based play interaction.
| Original language | English (US) |
|---|---|
| Article number | 107712 |
| Journal | Biological Psychology |
| Volume | 146 |
| DOIs | |
| State | Published - Sep 2019 |
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Keywords
- Autism spectrum disorder
- Automated behavioral assessment
- Parent-child interaction
- Play-based assessment
- Video tracking
ASJC Scopus subject areas
- Neuroscience(all)
- Neuropsychology and Physiological Psychology
Cite this
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Methodological considerations in the use of Noldus EthoVision XT video tracking of children with autism in multi-site studies. / Autism Biomarkers Consortium for Clinical Trials.
In: Biological Psychology, Vol. 146, 107712, 09.2019.Research output: Contribution to journal › Article
TY - JOUR
T1 - Methodological considerations in the use of Noldus EthoVision XT video tracking of children with autism in multi-site studies
AU - Autism Biomarkers Consortium for Clinical Trials
AU - Sabatos-DeVito, M.
AU - Murias, Michael
AU - Dawson, Geraldine
AU - Howell, Toni
AU - Yuan, Andrew
AU - Marsan, Samuel
AU - Bernier, Raphael A.
AU - Brandt, Cynthia A.
AU - Chawarska, Katarzyna
AU - Dzuira, James D.
AU - Faja, S.
AU - Jeste, Shafali S.
AU - Naples, Adam
AU - Nelson, Charles A.
AU - Shic, Frederick
AU - Sugar, Catherine A.
AU - Webb, Sara J.
AU - McPartland, James C.
PY - 2019/9
Y1 - 2019/9
N2 - Animal models of autism spectrum disorders (ASD) contribute to understanding of the role of genetics and the biological mechanisms underlying behavioral phenotypes and inform the development of potential treatments. Translational biomarkers are needed that can both validate these models and facilitate behavioral testing paradigms for ASD in humans. Automated video tracking of movement patterns and positions recorded from overhead cameras is routinely applied in behavioral paradigms designed to elicit core behavioral manifestations of ASD in rodent models. In humans, laboratory-based observations are a common semi-naturalistic context for assessing a variety of behaviors relevant to ASD such as social engagement, play, and attention. We present information learned and suggest guidelines for designing, recording, acquiring, and evaluating video tracking data of human movement patterns based on our experience in a multi-site video tracking study of children with ASD in the context of a parent-child, laboratory-based play interaction.
AB - Animal models of autism spectrum disorders (ASD) contribute to understanding of the role of genetics and the biological mechanisms underlying behavioral phenotypes and inform the development of potential treatments. Translational biomarkers are needed that can both validate these models and facilitate behavioral testing paradigms for ASD in humans. Automated video tracking of movement patterns and positions recorded from overhead cameras is routinely applied in behavioral paradigms designed to elicit core behavioral manifestations of ASD in rodent models. In humans, laboratory-based observations are a common semi-naturalistic context for assessing a variety of behaviors relevant to ASD such as social engagement, play, and attention. We present information learned and suggest guidelines for designing, recording, acquiring, and evaluating video tracking data of human movement patterns based on our experience in a multi-site video tracking study of children with ASD in the context of a parent-child, laboratory-based play interaction.
KW - Autism spectrum disorder
KW - Automated behavioral assessment
KW - Parent-child interaction
KW - Play-based assessment
KW - Video tracking
UR - http://www.scopus.com/inward/record.url?scp=85068266394&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85068266394&partnerID=8YFLogxK
U2 - 10.1016/j.biopsycho.2019.05.012
DO - 10.1016/j.biopsycho.2019.05.012
M3 - Article
C2 - 31163191
AN - SCOPUS:85068266394
VL - 146
JO - Biological Psychology
JF - Biological Psychology
SN - 0019-493X
M1 - 107712
ER -