Methodological considerations in the use of Noldus EthoVision XT video tracking of children with autism in multi-site studies

Autism Biomarkers Consortium for Clinical Trials

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Animal models of autism spectrum disorders (ASD) contribute to understanding of the role of genetics and the biological mechanisms underlying behavioral phenotypes and inform the development of potential treatments. Translational biomarkers are needed that can both validate these models and facilitate behavioral testing paradigms for ASD in humans. Automated video tracking of movement patterns and positions recorded from overhead cameras is routinely applied in behavioral paradigms designed to elicit core behavioral manifestations of ASD in rodent models. In humans, laboratory-based observations are a common semi-naturalistic context for assessing a variety of behaviors relevant to ASD such as social engagement, play, and attention. We present information learned and suggest guidelines for designing, recording, acquiring, and evaluating video tracking data of human movement patterns based on our experience in a multi-site video tracking study of children with ASD in the context of a parent-child, laboratory-based play interaction.

Original languageEnglish (US)
Article number107712
JournalBiological Psychology
Volume146
DOIs
StatePublished - Sep 2019

Fingerprint

Autistic Disorder
Rodentia
Animal Models
Biomarkers
Autism Spectrum Disorder
Guidelines
Phenotype
Therapeutics

Keywords

  • Autism spectrum disorder
  • Automated behavioral assessment
  • Parent-child interaction
  • Play-based assessment
  • Video tracking

ASJC Scopus subject areas

  • Neuroscience(all)
  • Neuropsychology and Physiological Psychology

Cite this

@article{c232ba5b9baf4f6d9421889c745ae2b0,
title = "Methodological considerations in the use of Noldus EthoVision XT video tracking of children with autism in multi-site studies",
abstract = "Animal models of autism spectrum disorders (ASD) contribute to understanding of the role of genetics and the biological mechanisms underlying behavioral phenotypes and inform the development of potential treatments. Translational biomarkers are needed that can both validate these models and facilitate behavioral testing paradigms for ASD in humans. Automated video tracking of movement patterns and positions recorded from overhead cameras is routinely applied in behavioral paradigms designed to elicit core behavioral manifestations of ASD in rodent models. In humans, laboratory-based observations are a common semi-naturalistic context for assessing a variety of behaviors relevant to ASD such as social engagement, play, and attention. We present information learned and suggest guidelines for designing, recording, acquiring, and evaluating video tracking data of human movement patterns based on our experience in a multi-site video tracking study of children with ASD in the context of a parent-child, laboratory-based play interaction.",
keywords = "Autism spectrum disorder, Automated behavioral assessment, Parent-child interaction, Play-based assessment, Video tracking",
author = "{Autism Biomarkers Consortium for Clinical Trials} and M. Sabatos-DeVito and Michael Murias and Geraldine Dawson and Toni Howell and Andrew Yuan and Samuel Marsan and Bernier, {Raphael A.} and Brandt, {Cynthia A.} and Katarzyna Chawarska and Dzuira, {James D.} and S. Faja and Jeste, {Shafali S.} and Adam Naples and Nelson, {Charles A.} and Frederick Shic and Sugar, {Catherine A.} and Webb, {Sara J.} and McPartland, {James C.}",
year = "2019",
month = "9",
doi = "10.1016/j.biopsycho.2019.05.012",
language = "English (US)",
volume = "146",
journal = "Biological Psychology",
issn = "0019-493X",
publisher = "Elsevier",

}

Methodological considerations in the use of Noldus EthoVision XT video tracking of children with autism in multi-site studies. / Autism Biomarkers Consortium for Clinical Trials.

In: Biological Psychology, Vol. 146, 107712, 09.2019.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Methodological considerations in the use of Noldus EthoVision XT video tracking of children with autism in multi-site studies

AU - Autism Biomarkers Consortium for Clinical Trials

AU - Sabatos-DeVito, M.

AU - Murias, Michael

AU - Dawson, Geraldine

AU - Howell, Toni

AU - Yuan, Andrew

AU - Marsan, Samuel

AU - Bernier, Raphael A.

AU - Brandt, Cynthia A.

AU - Chawarska, Katarzyna

AU - Dzuira, James D.

AU - Faja, S.

AU - Jeste, Shafali S.

AU - Naples, Adam

AU - Nelson, Charles A.

AU - Shic, Frederick

AU - Sugar, Catherine A.

AU - Webb, Sara J.

AU - McPartland, James C.

PY - 2019/9

Y1 - 2019/9

N2 - Animal models of autism spectrum disorders (ASD) contribute to understanding of the role of genetics and the biological mechanisms underlying behavioral phenotypes and inform the development of potential treatments. Translational biomarkers are needed that can both validate these models and facilitate behavioral testing paradigms for ASD in humans. Automated video tracking of movement patterns and positions recorded from overhead cameras is routinely applied in behavioral paradigms designed to elicit core behavioral manifestations of ASD in rodent models. In humans, laboratory-based observations are a common semi-naturalistic context for assessing a variety of behaviors relevant to ASD such as social engagement, play, and attention. We present information learned and suggest guidelines for designing, recording, acquiring, and evaluating video tracking data of human movement patterns based on our experience in a multi-site video tracking study of children with ASD in the context of a parent-child, laboratory-based play interaction.

AB - Animal models of autism spectrum disorders (ASD) contribute to understanding of the role of genetics and the biological mechanisms underlying behavioral phenotypes and inform the development of potential treatments. Translational biomarkers are needed that can both validate these models and facilitate behavioral testing paradigms for ASD in humans. Automated video tracking of movement patterns and positions recorded from overhead cameras is routinely applied in behavioral paradigms designed to elicit core behavioral manifestations of ASD in rodent models. In humans, laboratory-based observations are a common semi-naturalistic context for assessing a variety of behaviors relevant to ASD such as social engagement, play, and attention. We present information learned and suggest guidelines for designing, recording, acquiring, and evaluating video tracking data of human movement patterns based on our experience in a multi-site video tracking study of children with ASD in the context of a parent-child, laboratory-based play interaction.

KW - Autism spectrum disorder

KW - Automated behavioral assessment

KW - Parent-child interaction

KW - Play-based assessment

KW - Video tracking

UR - http://www.scopus.com/inward/record.url?scp=85068266394&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85068266394&partnerID=8YFLogxK

U2 - 10.1016/j.biopsycho.2019.05.012

DO - 10.1016/j.biopsycho.2019.05.012

M3 - Article

C2 - 31163191

AN - SCOPUS:85068266394

VL - 146

JO - Biological Psychology

JF - Biological Psychology

SN - 0019-493X

M1 - 107712

ER -