METHODS AND COMPOSITIONS FOR INHIBITING ANGIOGENESIS

Olga Volpert (Inventor)

Research output: Patent

Abstract

Fine Mapping of Pigment Epithelium-Derived Factor Anti-Angiogenic Activity NU 2007-084 Abstract Northwestern researchers have identified an alternate target for cancer therapy. While VEGF has shown some promise in the treatment of some cancers, it has not been successful in many other tumor types, suggesting that other factors or components play a critical role in suppressing tumor angiogenesis. The researchers have identified PEDF (pigment epithelium derived factor) to be an additional factor that can be used to modulate angiogenesis and treat angiogenesis-mediated disease. They have identified peptides derived from PEDF with potent suppressive function in eye disease and cancer. Applications o Therapeutics: Anti-Angiogenesis o Eye Disease IP Status Issued US Patent No. 8,198,406
Original languageEnglish
Patent number8198406
StatePublished - Dec 30 2010

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  • Cite this

    Volpert, O. (2010). METHODS AND COMPOSITIONS FOR INHIBITING ANGIOGENESIS. (Patent No. 8198406).