Methylene blue for burn-induced vasoplegia: Case report and review of literature

Joseph T. Church*, Joseph A. Posluszny, Mark Hemmila, Kathleen B. To, Jill R. Cherry-Bukowiec, Jennifer Waljee

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


We report the use of a single dose of methylene blue in a patient with burn-induced vasoplegia refractory to fluids, vasopressors, and steroids. Administration of methylene blue allowed for cessation of epinephrine infusion within 2 hours of administration, and reduction in excessive fluid resuscitation. The patient's clinical course continued for 2 months and was complicated by severe acute respiratory distress syndrome, pneumonia, septic shock, poor skin graft adherence, renal failure requiring continuous renal replacement therapy, cutaneous mucormycosis, and ultimately, withdrawal of care and death. Despite the eventual outcome, this is the longest reported survival following methylene blue administration for vasoplegia secondary to burn injury.

Original languageEnglish (US)
Pages (from-to)e107-e111
JournalJournal of Burn Care and Research
Issue number2
StatePublished - Feb 28 2015

ASJC Scopus subject areas

  • Surgery
  • Emergency Medicine
  • Rehabilitation

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