Abstract
We reviewed medical records of children with orbital cellulitis with positive cultures at a tertiary institution from 2005 to 2018 to identify microbiology trends and features associated with methicillin-resistant Staphylococcus aureus (MRSA) cases. Cultures obtained from the orbits (n = 33), sinuses (n = 31), and dural cavities (n = 4) had yields of 66.7%, 61.3%, and 75%, respectively, compared with 17.6% of blood cultures (n = 69). Fifty-five patients had positive culture results. Staphylococcus aureus was the most common pathogen isolated (n = 19), followed by Streptococcus species, most commonly Streptococcus anginosus (n = 8). The most frequently prescribed antibiotic combination regimen was ampicillin-sulbactam followed by amoxicillin-clavulanate. There were 8 cases of MRSA. MRSA was associated with an age of presentation <1 year old (P =.034). Other clinical features were similar between MRSA and non-MRSA cases. In infants and neonates, or those with epidemiologic risk factors, MRSA should also be considered.
Original language | English (US) |
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Pages (from-to) | 1056-1062 |
Number of pages | 7 |
Journal | Clinical pediatrics |
Volume | 58 |
Issue number | 10 |
DOIs | |
State | Published - Sep 1 2019 |
Keywords
- antibiotics
- methicillin-resistant Staphylococcus aureus
- microbiology
- orbital cellulitis
- pediatric
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
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Microbiology of Pediatric Orbital Cellulitis and Trends in Methicillin-Resistant Staphylococcus aureus Cases
Hsu, J. (Creator), Treister, A. D. (Creator), Ralay Ranaivo, H. (Contributor), Rowley, A. H. (Creator) & Rahmani, B. (Creator), figshare, 2019
DOI: 10.25384/sage.c.4581260.v1, https://sage.figshare.com/collections/Microbiology_of_Pediatric_Orbital_Cellulitis_and_Trends_in_Methicillin-Resistant_i_Staphylococcus_aureus_i_Cases/4581260/1
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