Microbiology of Pediatric Orbital Cellulitis and Trends in Methicillin-Resistant Staphylococcus aureus Cases

Jerry Hsu, Alison D. Treister, Hantamalala Ralay Ranaivo, Anne H Rowley, Bahram Rahmani*

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

We reviewed medical records of children with orbital cellulitis with positive cultures at a tertiary institution from 2005 to 2018 to identify microbiology trends and features associated with methicillin-resistant Staphylococcus aureus (MRSA) cases. Cultures obtained from the orbits (n = 33), sinuses (n = 31), and dural cavities (n = 4) had yields of 66.7%, 61.3%, and 75%, respectively, compared with 17.6% of blood cultures (n = 69). Fifty-five patients had positive culture results. Staphylococcus aureus was the most common pathogen isolated (n = 19), followed by Streptococcus species, most commonly Streptococcus anginosus (n = 8). The most frequently prescribed antibiotic combination regimen was ampicillin-sulbactam followed by amoxicillin-clavulanate. There were 8 cases of MRSA. MRSA was associated with an age of presentation <1 year old (P =.034). Other clinical features were similar between MRSA and non-MRSA cases. In infants and neonates, or those with epidemiologic risk factors, MRSA should also be considered.

Original languageEnglish (US)
Pages (from-to)1056-1062
Number of pages7
JournalClinical pediatrics
Volume58
Issue number10
DOIs
StatePublished - Sep 1 2019

Fingerprint

Orbital Cellulitis
Methicillin-Resistant Staphylococcus aureus
Microbiology
Pediatrics
Staphylococcus aureus
Streptococcus anginosus
Epidemiologic Factors
Clavulanic Acid
Amoxicillin
Orbit
Streptococcus
Medical Records
Newborn Infant
Anti-Bacterial Agents

Keywords

  • antibiotics
  • methicillin-resistant Staphylococcus aureus
  • microbiology
  • orbital cellulitis
  • pediatric

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Hsu, Jerry ; Treister, Alison D. ; Ralay Ranaivo, Hantamalala ; Rowley, Anne H ; Rahmani, Bahram. / Microbiology of Pediatric Orbital Cellulitis and Trends in Methicillin-Resistant Staphylococcus aureus Cases. In: Clinical pediatrics. 2019 ; Vol. 58, No. 10. pp. 1056-1062.
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Microbiology of Pediatric Orbital Cellulitis and Trends in Methicillin-Resistant Staphylococcus aureus Cases. / Hsu, Jerry; Treister, Alison D.; Ralay Ranaivo, Hantamalala; Rowley, Anne H; Rahmani, Bahram.

In: Clinical pediatrics, Vol. 58, No. 10, 01.09.2019, p. 1056-1062.

Research output: Contribution to journalArticle

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