Following CPIB treatment one or more double-walled tubular structures, measuring 110 μ in diameter, were observed in the hepatic microbody profiles in hypophysectomized rats, as well in rats bearing liver tumors. These tubules appeared as straight rigid rods of considerable length and were oriented irregularly within the microbody profiles. Examination of several microbody profiles containing these tubules suggests that these structures may be formed as a result of transformation of microbody matrix protein(s). Varying degrees of electron lucency of microbody matrix and the size and shape of the channels containing these straight tubules are considered as further evidence to indicate that microbody proteins circulate within the endoplasmic reticulum channels.
ASJC Scopus subject areas
- Pathology and Forensic Medicine