Microcantilever resonance-based DNA detection with nanoparticle probes

Ming Su, Shuyou Li, Vinayak P. Dravida*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

238 Scopus citations

Abstract

The DNA strands were detected using microcantilevers with a specific sequence using gold nanoparticle modified DNA. The shift of the cantilever frequency signalled the binding events after the amplification process by catalyzing the nucleation of silver. Results showed that multiple DNA detection is possible by coating multiple cantilevers with various capture DNA strands and monitoring the change in their resonance frequencies.

Original languageEnglish (US)
Pages (from-to)3562-3564
Number of pages3
JournalApplied Physics Letters
Volume82
Issue number20
DOIs
StatePublished - May 19 2003

ASJC Scopus subject areas

  • Physics and Astronomy (miscellaneous)

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