Microcystic/reticular schwannoma: Morphological features causing diagnostic dilemma on fine-needle aspiration cytology

Shunyou Gong, Said Hafez-Khayyata, Wei Xin*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Case Report: A 28-year-old male presented with right arm and finger tingling and numbness. Physical examination found a right lower neck mass. He underwent FNA, followed by needle core biopsy. A diagnosis of microcystic/reticular schwannoma was made. In this case report, we focused on the FNA diagnostic features, thoroughly searched the literature, and discussed relevant information for differential diagnosis.

Conclusions: Unlike classic Schwannoma, microcystic/reticular variant has unique cytological features which can mimic those of several morphologically similar mass lesions, making the FNA interpretation more challenging. Cytopathologists should be aware of this new variant of Schwannoma when evaluating FNA cytology of mass lesions showing low-grade, paucicellular, and myxoid features.

Objective: Rare disease

Background: Schwannoma is a common, benign, peripheral nerve sheath tumor. Fine-needle aspiration (FNA) has been very useful for diagnosing classic Schwannoma. Recently, a new morphological variant, the so-called microcystic/re-ticular Schwannoma, has been recognized. Although histological features of microcystic/reticular Schwannoma have been described, there are no available reports on its FNA cytological appearance.

Original languageEnglish (US)
Pages (from-to)538-542
Number of pages5
JournalAmerican Journal of Case Reports
Volume15
DOIs
StatePublished - Dec 4 2014

Keywords

  • Biopsy
  • Diagnosis
  • Fine-Needle
  • Neurilemmoma

ASJC Scopus subject areas

  • Medicine(all)

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