Microfluidic immunophenotyping assay platform for immunomonitoring of subpopulations of immune cells

W. Chen, N. Huang, B. Oh, T. T. Cornell, T. P. Shanley, K. Kurabayashi, J. Fu*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Functional immunophenotyping of immune cells is a promising method for diagnosis of immune dysfunctions. In this study, an integrated microfluidic immunophenotyping device was developed that could achieve rapid and efficient isolation, enrichment, stimulation and functional immunophenotyping of subpopulations of immune cells directly from blood specimens. This new microfluidic immunophenotyping technology can provide an unprecedented level of information depth on the distribution of immune cell functionalities. Such an innovative tool will allow comprehensive and systems-level immunomonitoring to define and characterize the "immune status" of healthy individuals and patients, critical for clinical interventions and managements of patients with immune system disorders.

Original languageEnglish (US)
Title of host publication17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
PublisherChemical and Biological Microsystems Society
Pages1761-1763
Number of pages3
ISBN (Print)9781632666246
StatePublished - Jan 1 2013
Event17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 - Freiburg, Germany
Duration: Oct 27 2013Oct 31 2013

Publication series

Name17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
Volume3

Other

Other17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
CountryGermany
CityFreiburg
Period10/27/1310/31/13

Keywords

  • Cytokines
  • Immune cells
  • Immunophenotyping
  • Microfluidics

ASJC Scopus subject areas

  • Bioengineering

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  • Cite this

    Chen, W., Huang, N., Oh, B., Cornell, T. T., Shanley, T. P., Kurabayashi, K., & Fu, J. (2013). Microfluidic immunophenotyping assay platform for immunomonitoring of subpopulations of immune cells. In 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 (pp. 1761-1763). (17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013; Vol. 3). Chemical and Biological Microsystems Society.