@inproceedings{7048215a59014495a543a217599b2e0e,
title = "Microfluidic platforms for on-chip formulation and small-angle X-ray analysis of the phase behavior of lipid/water mixtures",
abstract = "We present a microfluidic platform for on-chip formulation and X-ray analysis of lipidic mesophases formed upon mixing lipids and water. The platform is designed to study the effect of detergents on the phase behavior of lipid/water mixtures. The platform allows automated preparation of multiple samples of different composition from stock solutions and subsequent on-chip small-angle X-ray diffraction (SAXS) data collection. To ensure X-ray transparency of the platform we used thin layers of cyclic olefin copolymer (COC) and PDMS. The viability of the platform is demonstrated by mapping out a section of the phase diagram for lipid monoolein mixed with solutions of detergent β-octylglucoside.",
keywords = "Microfluidics, Monoolein, Phase diagrams, SAXS, X-ray transparent chips",
author = "Khvostichenko, {Daria S.} and Perry, {Sarah L.} and Elena Kondrashkina and Sudipto Guha and Keith Brister and Kenis, {Paul J.A.}",
year = "2011",
language = "English (US)",
isbn = "9781618395955",
series = "15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011",
pages = "1403--1405",
booktitle = "15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011",
note = "15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 ; Conference date: 02-10-2011 Through 06-10-2011",
}