Microfluidic platforms with monolithically integrated hierarchical apertures for the facile and rapid formation of cargo-carrying vesicles

Hyesung Cho; Junsoo Kim; Keishi Suga; Takaaki Ishigami; Hyunchul Park; Jung Won Bang; Soonmin Seo; Mansoo Choi; Pahn Shick Chang; Hiroshi Umakoshi; Ho Sup Jung; Kahp Yang Suh

doi:10.1039/c4lc01096e

Microfluidic platforms with monolithically integrated hierarchical apertures for the facile and rapid formation of cargo-carrying vesicles

Hyesung Cho, Junsoo Kim, Keishi Suga, Takaaki Ishigami, Hyunchul Park, Jung Won Bang, Soonmin Seo, Mansoo Choi, Pahn Shick Chang, Hiroshi Umakoshi^*, Ho Sup Jung, Kahp Yang Suh

^*Corresponding author for this work

Mechanical Engineering

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

We fabricated a simple yet robust microfluidic platform with monolithically integrated hierarchical apertures. This platform showed efficient diffusive mixing of the introduced lipids through approximately 8000 divisions with tiny pores (~5 μm in diameter), resulting in massive, real-time production of various cargo-carrying particles via multi-hydrodynamic focusing.

Original language	English (US)
Pages (from-to)	373-377
Number of pages	5
Journal	Lab on a Chip
Volume	15
Issue number	2
DOIs	https://doi.org/10.1039/c4lc01096e
State	Published - Jan 21 2015

ASJC Scopus subject areas

Bioengineering
Biochemistry
General Chemistry
Biomedical Engineering

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10.1039/c4lc01096e

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title = "Microfluidic platforms with monolithically integrated hierarchical apertures for the facile and rapid formation of cargo-carrying vesicles",

abstract = "We fabricated a simple yet robust microfluidic platform with monolithically integrated hierarchical apertures. This platform showed efficient diffusive mixing of the introduced lipids through approximately 8000 divisions with tiny pores (~5 μm in diameter), resulting in massive, real-time production of various cargo-carrying particles via multi-hydrodynamic focusing.",

author = "Hyesung Cho and Junsoo Kim and Keishi Suga and Takaaki Ishigami and Hyunchul Park and Bang, {Jung Won} and Soonmin Seo and Mansoo Choi and Chang, {Pahn Shick} and Hiroshi Umakoshi and Jung, {Ho Sup} and Suh, {Kahp Yang}",

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AU - Cho, Hyesung

AU - Kim, Junsoo

AU - Suga, Keishi

AU - Ishigami, Takaaki

AU - Park, Hyunchul

AU - Bang, Jung Won

AU - Seo, Soonmin

AU - Choi, Mansoo

AU - Chang, Pahn Shick

AU - Umakoshi, Hiroshi

AU - Jung, Ho Sup

AU - Suh, Kahp Yang

PY - 2015/1/21

Y1 - 2015/1/21

N2 - We fabricated a simple yet robust microfluidic platform with monolithically integrated hierarchical apertures. This platform showed efficient diffusive mixing of the introduced lipids through approximately 8000 divisions with tiny pores (~5 μm in diameter), resulting in massive, real-time production of various cargo-carrying particles via multi-hydrodynamic focusing.

AB - We fabricated a simple yet robust microfluidic platform with monolithically integrated hierarchical apertures. This platform showed efficient diffusive mixing of the introduced lipids through approximately 8000 divisions with tiny pores (~5 μm in diameter), resulting in massive, real-time production of various cargo-carrying particles via multi-hydrodynamic focusing.

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Microfluidic platforms with monolithically integrated hierarchical apertures for the facile and rapid formation of cargo-carrying vesicles

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