Microlithiasis, endoscopic ultrasound, and children: Not just little gallstones in little adults

Lucas P. Neff, Girish Mishra, John E. Fortunato, Jennifer Laudadio, John K. Petty

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Purpose: Biliary microlithiasis is an uncommon but recognized cause of upper abdominal pain, cholecystitis, cholangitis, and pancreatitis in adults. Gallstones smaller than 3 mm may not be seen on transabdominal ultrasound and may only be seen on endoscopic ultrasound. This condition is poorly described in children. The aim of this study is to review the results of laparoscopic cholecystectomy to treat biliary microlithiasis in a pediatric case series. Methods: We performed a retrospective case review of children with biliary microlithiasis who were treated with laparoscopic cholecystectomy. Results: Three children were diagnosed with biliary microlithiasis. Two patients had recurrent right upper quadrant pain and nausea. A third patient had midepigastric pain and idiopathic pancreatitis. All 3 had a normal gallbladder on transabdominal ultrasound. Additional imaging with hepatobiliary scan, computed tomography, and magnetic resonance cholangiopancreatography revealed no biliary source for symptoms. Endoscopic ultrasound was performed on all 3 children, demonstrating microlithiasis of the gallbladder. Each child had a laparoscopic cholecystectomy with intraoperative cholangiogram. No abnormalities were seen on intraoperative cholangiogram. All 3 children had alleviation of pain and improvement of symptoms in postoperative follow-up. Conclusion: Children with biliary microlithiasis and associated clinical symptoms can be successfully treated with laparoscopic cholecystectomy. Endoscopic ultrasound should be considered in the evaluation of the child with clinical biliary symptoms and a negative transabdominal ultrasound result.

Original languageEnglish (US)
Pages (from-to)462-466
Number of pages5
JournalJournal of pediatric surgery
Issue number3
StatePublished - Mar 1 2011


  • Abdominal pain
  • Biliary microlithiasis
  • Child
  • Endoscopic ultrasound
  • Gallstones
  • Laparoscopic cholecystectomy

ASJC Scopus subject areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health


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