Abstract
This work presents the microring resonator based disposable ultrasound-sensing chronic cranial window. We optimized the sensor design and the fabrication to significantly improve detection sensitivity and reliability for biomedical applications.
| Original language | English (US) |
|---|---|
| Article number | OM2D.7 |
| Journal | Optics InfoBase Conference Papers |
| State | Published - 2022 |
| Event | Optical Tomography and Spectroscopy, OTS 2022 - Fort Lauderdale, United States Duration: Apr 24 2022 → Apr 27 2022 |
Funding
[1] A. Holtmaat et al. Long-term, “high-resolution imaging in the mouse neocortex through a chronic cranial window,” Nature Protocols 4, 1128-1144 (2009). [2] G. J. Goldey et al. “Removable cranial windows for long-term imaging in awake mice.” Nature Protocols 9, 2515-2538 (2014). [3] M. Alieva, L. Ritsma, R. J. Giedt, R. Weissleder, and J. van Rheenen, “Imaging windows for long-term intravital imaging: General overview and technical insights,” IntraVital 3, e29917 (2014). [4] C. Heo et al. A soft, transparent, freely accessible cranial window for chronic imaging and electrophysiology. Scientific Reports 6, 27818 (2016). Acknowledgement This work was supported by grants of the NIH (P41GM135018) and DOE, Office of Science (DE-AC02-06CH1135).
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Mechanics of Materials