Microvascular surgery in a bloodless field

Gregory A. Dumanian*, Alexandria Chen

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Although tourniquets play an integral role in extremity surgery, no clear guidelines exist for the use of tourniquets in microsurgery. We undertook a study in 12 healthy volunteers to better understand the coagulation properties of blood distal to an inflated tourniquet. At a 15-min inflation time, blood distal to an inflated tourniquet clots faster than blood taken from the opposite arm after addition of exogenous thrombin (12.5 s vs 17.5 s, P < 0.0001). Neither fibrinopeptide A (FPA) levels nor tissue plasminogen activator (tPA) levels were different from those of controls. Tissue factor pathway inhibitor (TFPI), an endogenous local anticoagulant, was slightly but significantly elevated in tourniquet blood. Although much remains to be understood, we believe that microvascular surgery in a bloodless field is safe and efficacious. Nine patients are presented who successfully underwent microvascular surgery in a bloodless field, using various types of extremity tourniquets.

Original languageEnglish (US)
Pages (from-to)221-224
Number of pages4
Issue number5
StatePublished - Oct 7 2000

ASJC Scopus subject areas

  • Surgery


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